ChemicalBook >>Spironolactone>>17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate(52-01-7)

17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate(52-01-7)

17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate(52-01-7)
Product IdentificationBack to Contents
【Product Name】

17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate
【Synonyms】

3-(3-Oxo-7a-acetylthio-17b-hydroxy-4-androsten-17a-yl)propionic acid-g-lactone
3'-(3-Oxo-7a-acetylthio-17b-hydroxyandrost-4-en-17a-yl)-propionic acid lactone
Nefurofan
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, g-lactone, (7a,17a)-
Verospirone
【CAS】

52-01-7
【Formula】

C24H32O4S
【Molecular Weight】

416.58
【EINECS】

200-133-6
【RTECS】

TU4725000
【RTECS Class】

Tumorigen; Drug; Reproductive Effector; Human Data
【Merck】

12,8917
【Beilstein/Gmelin】

57767
【Beilstein Reference】

4-18-00-01601
Physical and Chemical PropertiesBack to Contents
【Appearance】

White powder.
【Solubility in water】

Insoluble
【Melting Point】

196
【Boiling Point】

597
【Vapor Pressure】

3E-14 (25 C)
【Partition Coefficient】

3.12
【Heat Of Vaporization】

88.9 kJ/mol
【Usage】

Diuretic.
First Aid MeasuresBack to Contents
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood. Do not breathe dust.
Hazards IdentificationBack to Contents
【Ingestion】

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Other human systemic effects by ingestion: agranulocytosis, kidney tubule damage, increased urine volume, and changes in blood sodium and calcium levels.
【Inhalation】

May cause respiratory tract irritation. May cause irritation of the mucous membranes.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Fire Fighting MeasuresBack to Contents
【Flash Point】

302
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, oxides of sulfur, carbon dioxide.
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