文章标题：Antibacterial activity of corydalis saxicola bunting total alkaloids against Porphyromonas gingivalis in vitro
期刊：Future Microbiology
作者列表：Wenli Ye, Jiaxuan Wu, Qiaozhi Jiang, Zhiheng Su, Haiqing Liao, Zhenmin Liu, Renchuan Tao, Xiangzhi Yong
发表时间：2024-4-17
影响因子：2.533
DOI:10.2217/fmb-2023-0165
主要研究成果Abstract
Background
Discs large homolog 2 (DLG2) has been implicated in cancer development, yet its role in cervical cancer remains unclear. This study aims to explore the regulatory mechanism of DLG2 in cervical cancer and its clinical implications.
Methods
Quantitative reverse transcription polymerase chain reaction and western blotting assays were employed to detect RNA and protein expression, respectively. Colony formation assay, 5-Ethynyl-2’-deoxyuridine assay, flow cytometry, and transwell assays were conducted for cell functional analysis. A xenograft mouse model assay was performed to analyze tumor tumorigenesis in vivo. m6A RNA immunoprecipitation assay was used to analyze the association of METTL3 and DLG2.