Coenzyme Q10 is a small molecule fat soluble quinone organic compound that widely exists in animal and plant cells. Its structure is similar to that of vitamin K. It is a strong antioxidant when used alone or in combination with vitamin E.
pharmacological action
1. It can alleviate the weakening of myocardial contractility and the reduction of phosphocreatine and adenosine triphosphate content during acute ischemia, maintain the morphological structure of mitochondria in ischemic myocardial cells, and have a certain protective effect on ischemic myocardium.
2. Increasing cardiac output and reducing peripheral resistance are beneficial to the treatment of heart failure, which may inhibit the synthesis and secretion of aldosterone and block its effect on renal tubules.
3. When the isolated ventricular muscles of animals were perfused under hypoxia, the duration of action potential was shortened, and the threshold of ventricular arrhythmia was higher than that of control animals.
4. It can reduce peripheral vascular resistance and have an anti aldosterone effect.
5. Coenzyme Q10 has cardiotoxic and liver protective effects against doxorubicin.
application
1. Pharmaceutical industry: treating heart failure and dilated cardiomyopathy; Lower blood pressure and blood lipids; Antioxidant activity, cardiovascular system applications; Treatment of congestive heart failure; Used for postoperative treatment of heart disease surgery; Delaying the development of heart failure and reducing mortality. A significant feature of coenzyme Q10 is its non-toxicity, no teratogenic effects, and no obvious side effects, making it highly safe in clinical practice.
2. Cosmetics industry: Delaying skin aging, wrinkle removal, whitening, and moisturizing, safe and non irritating to the human body.
3. Health care products industry: anti fatigue, with the function of protecting and restoring the integrity of biological membrane structure, stabilizing membrane potential, it is a non-specific immune enhancer of the body, so it shows excellent anti fatigue effect, keeping cells in good health.
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