已验证抗体 * 退换有保障
Rabbit Polyclonal Antibody to CYP1A1
Catalog No.：FA04799 【Specification】
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Fusion protein of human CYP1A1
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
【Description】
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily ofenzymes. The cytochrome P450 proteins are monooxygenases which catalyze manyreactions involved in drug metabolism and synthesis of cholesterol, steroids andother lipids. This protein localizes to the endoplasmic reticulum and its expressionis induced by some polycyclic aromatic hydrocarbons (PAHs), some of which arefound in cigarette smoke. The enzyme's endogenous substrate is unknown;however, it is able to metabolize some PAHs to carcinogenic intermediates. Thegene has been associated with lung cancer risk. A related family member, CYP1A2,is located approximately 25 kb away from CYP1A1 on chromosome 15.
【Application】
For Research Only-Time Saved, Science Advanced苏州丰度蛋白生物技术有限公司（www.fedprotein.com)
Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Mouse liver tissue,
Primary antibody: (CYP1A1 Antibody) at dilution 1/400, Secondary
antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5
seconds
The image is immunohistochemistry of paraffin-embedded
Human liver cancer tissue using (CYP1A1 Antibody) at
dilution 1/25. (Original magnification: ×200)