Jena bioscience--2-Thio-UTP：s、2UTP、2-硫代-UTP、2-硫尿苷-5'-三磷酸钠盐Cat. No. Amount
NU-1151S 10 µl (100 mM)
NU-1151L 5 x 10 µl (100 mM)
艾美捷2-Thio-UTP：
货号：NU-1151L
运输：使用凝胶包装运输
储存条件：需在-20°C下储存，可以短期（累计不超过1周）暴露在室温下。
保质期：自交货日期起12个月
分子式：C9H15N2O14P3S（游离酸）
分子量：500.21 g/mol（游离酸）
精确质量：499.95 g/mol（游离酸）
CAS号：35763-29-2
纯度：≥ 95%（高效液相色谱法）
形态：水溶液
颜色：无色至微黄
浓度：100 mM - 110 mM
pH值：7.5 ±0.5
光谱特性：最大吸收波长274 nm，摩尔吸光系数14.2 L mmol^-1 cm^-1（Tris-HCl pH 7.5）
特定配体：
用于嘌呤能受体的配体：
在P2Y2受体上具有强效和选择性的激动剂[1,2,3,4]
相关产品：
高产T7 RNA合成试剂盒，#RNT-101
2-Thio-UTP参考文献：
[1] Higgins et al. (2014) Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes. Mediators Inflamm. 293925.
[2] Zizzo M. et al. (2012) Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum. Purinergic Signal. 8 (2):275.
[3] Ko et al. (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg. Med. Chem. 16 (12):6319.
[4] El-Tayeb et al. (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. J. Med. Chem. 49 (24):7076.
Kormann et al. (2011) Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nature Biotechnology 29:154.
Warren et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7 (5):618
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