English name: Tadalafil(cialis)
CAS No.: 171596-29-5
Molecular formula: C22H19N3O4
Molecular weight: 389.4
EINECS number: 687-782-2
Melting point 298-300 ° C
Flash point 2°C
Storage conditions Hygroscopic, -20?C Freezer, Under Inert Atmosphere
Solubility DMSO: soluble20mg/mL, clear
Cialis is tadalafil. It is an oral drug for the treatment of male erectile dysfunction developed by Eli Lilly pharmaceutical company. It is a second-generation phosphodiesterase 5 inhibitor. The research report shows that compared with sildenafil, silex takes effect very quickly, about 15 ~ 20 minutes, and the effect is long, up to 36 hours. T1 / 2 is 17.5h. In a study involving 348 men with mild to severe erectile dysfunction, patients were randomized to tadalafil 20mg or placebo. The results showed that compared with placebo, the success of sexual intercourse after 24 and 36 hours was improved, and most men could have two successful sexual intercourse within 36 hours, There was no difference in the incidence and severity of adverse drug reactions compared with placebo. Headache and dyspepsia occurred in more than 5% of men in tadalafil group.
Purpose phosphodiesterase 5 inhibitor is used to treat male erectile dysfunction. The second generation phosphodiesterase 5 inhibitor is used to treat male Bo erectile dysfunction.