Host:Rabbit
Target Protein:ERK2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:5594
Swiss Prot:P28482
Source:Recombinant human ERK2 protein, around C-terminal 150aa:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1ug/Test)
ICC(1:100)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
.
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！