Product Name：GLP-1(7-36)
CAS No.：89750-14-1；107444-51-9
Synonyms：GLP-1-(7-36) amide；Glucagon-like peptide I；胰高血糖素样肽7-36
Catalog No.：153P05
Brand：HongTide（上海鸿肽生物）
Description：GLP-1是人体分泌的一种肠道激素，由胰高血糖素原(Proglucagon)分子经肠道蛋白水解酶作用而产生，因而称为胰高血糖素类多肽或胰高血糖素样肽，GLP-1(7-36)是其中的一种。生物体内的GLP-1有二种形式，一种为GLP-1(7-36)，是由30个氨基酸残基组成的多肽，肽链C端乙酰化；另一种为GLP-1(7-37)，是由31个氨基酸残基组成的多肽。GLP-1(7-36)和GLP-1(7-37)有相同的促胰岛素分泌作用。研究表明当血糖浓度高于6mmol/L时，GLP-1能显著促进胰岛素分泌；而一旦血糖浓度恢复至正常值则不再继续作用，在临床上这一点对II型糖尿病的治疗十分有用。
GLP-1 is an intestinal hormone secreted by the human body, which is produced by the action of Glucagon molecule through intestinal protein Hydrolase, so it is called Glucagon like peptide or Glucagon like peptide. GLP-1 (7-36) is one of them. There are two forms of GLP-1 in living organisms, one is GLP-1 (7-36), which is a peptide composed of 30 amino acid residues and acetylated at the C-end of the peptide chain; The other type is GLP-1 (7-37), which is a peptide composed of 31 amino acid residues. GLP-1 (7-36) and GLP-1 (7-37) have the same proinsulin secretion effect. Research has shown that GLP-1 can significantly promote insulin secretion when blood glucose concentration is higher than 6mmol/L; Once the blood glucose concentration returns to the normal value, it will not continue to function, which is very useful for the treatment of type II diabetes clinically.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 |
Sequence(3-letter code) | H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 |
Peptide Structure | 
|
Molecular Formula | C149H226N40O45 |
Molecular Weight | 3297.68 |
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关键字： 107444-51-9;89750-14-1;GLP-1(7-36) ;胰高血糖素样肽7-36;Glucagon-like peptid;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。