Rabbit Anti-GST1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GST1
IR:Immunogen Range:151-218/218
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2944
Swiss Prot:P09488
Source:KLH conjugated synthetic peptide derived from human GST1:151-218/218
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： GST1;Glutathione S-Transf;Glutathione S-Transf;GST HB Subunit 4;GST Class-Mu 1;EC 2.5.1.18;GSTM1a-1a;GSTM1_HUMAN;
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