Rabbit Anti-CD27 Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CD27
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:939
Swiss Prot:P26842
Source:KLH conjugated synthetic peptide derived from human CD27:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1:50-100)
ICC(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CD27;CD27 antigen;CD27 molecule;CD27L receptor;LPFS2;MGC20393;Tp55;CD27_HUMAN;
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