Rabbit Anti-STAT6 Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:STAT6
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:6778
Swiss Prot:P42226
Source:Recombinant human STAT6 protein, around 700-800aa:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:100-500)
IHC-F(1:20-200)
Flow-Cyt(2ug/Test)
ICC(1:20-200)
IF(1:20-200)
Cross Reactive Species:Human
Mouse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： STAT6;D12S1644;IL 4 STAT;Interleukin 4 Induce;STAT6B;STAT6C; Transcription facto;信号转导和转录激活因子6重组兔单抗;
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