aladdin 阿拉丁 N413659 NE 52-QQ57 1401728-56-0 98%

中文名：NE 52-QQ57

英文名：NE 52-QQ57

纯度：Moligand™，≥98%

货号：N413659

Cas号：1401728-56-0

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

NE 52-QQ57 is a selective, and orally available antagonist ofG-protein coupled receptor 4 (GPR4)with IC50 of 0.07 μM. NE 52-QQ57 effectively blocks GPR4-mediated cAMP accumulation with IC50 of 26.8 nM in HEK293 cells. The antagonism of GPR4 with NE 52-QQ57 significantly inhibits the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, includingtumor necrosis factor-α (TNF-α),interleukin (IL)-1β,IL-6,inducible nitric

Targets

TNF-α ; IL-1β ; IL-6 ; iNOS ; NO 33706,;

查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/N413659.html