中文名:CLP-290,K + / Cl-共转运蛋白2(KCC2)激活剂
英文名:CLP-290
中文别名:[5-Fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl] pyrrolidine-1-carboxylate;CLP290
英文别名:[5-Fluoro-2-[(Z)-(2-hexahydropyridazin-1-yl-4-oxo-thiazol-5-ylidene)methyl]phenyl] pyrrolidine-1-carboxylate;CLP290
纯度:97%
货号:C172342
包装:100mg、25mg
Cas号:1181083-81-7
存储温度:2-8°C储存
产品介绍:
CLP290 is a small molecule enhancer of KCC2 activity. It is an orally active and more bioavailable precursor of the selective K+-Cl- cotransporter KCC2 activator CLP257. CLP290 was recently shown to restore Cl- transport and rescue morphine-induced hyperalgesia (MIH) in morphine-treated rats
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