Product Name：CRAMP-18 (mouse)
CAS No.：256639-17-5
Synonyms：动物抗菌肽CRAMP-18 (mouse)trifluoroacetate salt
Catalog No.：112P15
Brand：HongTide（上海鸿肽生物）
Description：CRAMP是动物体内的抗菌肽，是由18个氨基酸组成的直链多肽，实验表明CRAMP具有促炎症的效果，在一些实验中，外源性CRAMP能够单独感与炎性细胞的趋化作用，同时能够增强小鼠肺部盐形细胞因子的分泌效果。鉴于细菌、真菌以及病毒感染等多种微生物入侵均有可能成为哮喘的诱发因子，而CRAMP则能够成为固有免疫的重要组成，广泛表达与肺部上皮细胞中，因此可以推断CRAMP可能在防治哮喘发生时起到重要研究作用。
CRAMP is an antimicrobial peptide in animal bodies, composed of 18 amino acids as a straight chain peptide. Experiments have shown that CRAMP has a pro-inflammatory effect. In some experiments, exogenous CRAMP can independently sense the chemotaxis of inflammatory cells and enhance the secretion of salt forming cytokines in mouse lungs. Given that various microbial invasions such as bacteria, fungi, and viral infections can all become triggering factors for asthma, and CRAMP can become an important component of innate immunity, widely expressed in lung epithelial cells, it can be inferred that CRAMP may play an important research role in the prevention and treatment of asthma.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GEKLKKIGQKIKNFFQKL |
Sequence(3-letter code) | H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH |
Peptide Structure | 
|
Molecular Formula | C101H171N27O24 |
Molecular Weight | 2147.64 |
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关键字： CRAMP-18 (mouse) ;256639-17-5;：动物抗菌肽CRAMP-18 (mous;多肽;多肽合成;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。