FGFR1OP抗体,Rabbit Polyclonal FGFR1OP Antibody
  • FGFR1OP抗体,Rabbit Polyclonal FGFR1OP Antibody
  • FGFR1OP抗体,Rabbit Polyclonal FGFR1OP Antibody
  • FGFR1OP抗体,Rabbit Polyclonal FGFR1OP Antibody

FGFR1OP抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-14
QQ交谈 微信洽谈

产品详情

中文名称:FGFR1OP抗体英文名称:Rabbit Polyclonal FGFR1OP Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4073 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: FGFR1OP
2025-05-14 FGFR1OP抗体 Rabbit Polyclonal FGFR1OP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4073 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesFOP
WB Predicted band size43 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human FGFR1OP
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse heart tissue, NIH/3T3 cells, mouse liver tissue, Primary antibody: P08329(FGFR1OP Antibody) at dilution 1/850, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P08329(FGFR1OP Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P08329(FGFR1OP Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于FGFR1OP抗体的参考文献示例(注:以下文献信息为模拟示例,实际文献需通过学术数据库验证):

1. **文献名称**: "FGFR1OP as a novel biomarker in acute myeloid leukemia: Development and validation of a specific monoclonal antibody"

**作者**: Smith A, et al.

**摘要**: 研究报道了一种针对FGFR1OP蛋白的单克隆抗体的开发,验证了其在白血病细胞系中的特异性结合能力,并证明其可用于AML患者的骨髓样本中FGFR1OP异常表达的检测。

2. **文献名称**: "Functional characterization of FGFR1OP in tumorigenesis using a polyclonal antibody-based approach"

**作者**: Chen L, et al.

**摘要**: 通过多克隆抗体研究FGFR1OP在肿瘤发生中的作用,发现其在调控细胞周期和DNA修复中的功能,抗体成功用于Western blot和免疫组化分析。

3. **文献名称**: "FGFR1OP interaction networks revealed by co-immunoprecipitation with a high-affinity antibody"

**作者**: Johnson R, et al.

**摘要**: 利用高亲和力抗体进行免疫共沉淀实验,揭示了FGFR1OP与多种染色质修饰蛋白的相互作用,为白血病中染色体易位机制提供了新见解。

4. **文献名称**: "A comparative study of FGFR1OP antibody performance in diagnostic immunohistochemistry"

**作者**: Wang Y, et al.

**摘要**: 比较了不同商业化FGFR1OP抗体在福尔马林固定组织中的表现,筛选出适用于临床病理诊断的高特异性抗体。

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建议通过PubMed或Web of Science检索真实文献(关键词:FGFR1OP antibody, FGFR1OP monoclonal antibody)以获取准确信息。

       

背景信息

The FGFR1OP (Fibroblast Growth Factor Receptor 1 Oncogenic Partner) antibody is a tool used to study the FGFR1OP protein, which is encoded by the *FGFR1OP* gene. This gene was initially identified as a partner in chromosomal translocations with the *FGFR1* gene in certain hematologic malignancies, particularly 8p11 myeloproliferative syndrome. The resulting fusion protein drives abnormal tyrosine kinase signaling, promoting oncogenesis. FGFR1OP itself is a conserved cytoplasmic protein implicated in cellular processes such as centrosome function, cytoskeletal organization, and cell cycle regulation, though its precise biological roles remain under investigation.

FGFR1OP antibodies are primarily utilized in research to detect and analyze the expression, localization, and interactions of FGFR1OP in normal and diseased tissues. They enable techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study FGFR1OP’s involvement in cancers, particularly those linked to FGFR1 rearrangements. Additionally, these antibodies help explore FGFR1OP’s potential role in non-cancer contexts, such as developmental biology or tissue repair. While not yet widely used in clinical diagnostics, FGFR1OP antibodies may hold future utility in identifying FGFR1-related malignancies or guiding targeted therapies. Their development and validation are critical for advancing understanding of FGFR1OP’s pathophysiological mechanisms and therapeutic relevance.

       
关键字: FGFR1OP抗体;FGFR1OP;FGFR1OP Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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