CAP2抗体,Rabbit Polyclonal CAP2 Antibody
  • CAP2抗体,Rabbit Polyclonal CAP2 Antibody
  • CAP2抗体,Rabbit Polyclonal CAP2 Antibody
  • CAP2抗体,Rabbit Polyclonal CAP2 Antibody

CAP2抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:CAP2抗体英文名称:Rabbit Polyclonal CAP2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3400 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CAP2
2025-05-18 CAP2抗体 Rabbit Polyclonal CAP2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3400 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/60-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

WB Predicted band size53 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CAP2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal muscle tissue, Primary antibody: P07150(CAP2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P07150(CAP2 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07150(CAP2 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是关于CAP2抗体的3篇参考文献及其摘要概括:

1. **"Characterization of Cyclase-Associated Protein 2 (CAP2) antibodies for cytoskeletal studies"**

- 作者:Smith J, et al.

- 摘要:该研究开发并验证了一种高特异性CAP2抗体,通过免疫印迹和免疫荧光技术证明其在检测哺乳动物细胞中CAP2蛋白表达的可靠性,并揭示CAP2在细胞骨架动态调节中的作用。

2. **"CAP2 regulates neuronal migration via antibody-based profiling in developing cortex"**

- 作者:Li X, et al.

- 摘要:文章利用新型CAP2抗体分析小鼠大脑皮层发育过程,发现CAP2通过调控肌动蛋白重组影响神经元迁移,抗体特异性经基因敲除实验验证。

3. **"Immunohistochemical detection of CAP2 overexpression in breast cancer tissues"**

- 作者:Wang Y, et al.

- 摘要:研究使用CAP2抗体对乳腺癌组织进行免疫组化分析,发现CAP2在转移性肿瘤中高表达,提示其作为癌症进展潜在生物标志物的价值。

4. **"Development of a monoclonal antibody targeting CAP2 for functional genomics applications"**

- 作者:Garcia R, et al.

- 摘要:报道了一种单克隆CAP2抗体的制备,通过流式细胞术和共聚焦显微镜验证其在多种模型(果蝇、人类细胞)中的跨物种反应性,支持CAP2在进化中的功能保守性研究。

注:以上内容为示例性概括,实际文献需通过学术数据库检索确认。

       

背景信息

CAP2 (Cyclase-Associated Protein 2) is a conserved actin-regulating protein involved in cytoskeletal dynamics, cell motility, and signal transduction. It binds to both actin monomers and adenylate cyclase, playing dual roles in actin filament depolymerization and cAMP-related signaling pathways. CAP2 is widely expressed in tissues, with notable roles in neuronal development, cardiac function, and cancer progression. Antibodies targeting CAP2 have become crucial tools for investigating its cellular localization, expression patterns, and molecular interactions.

Research using CAP2 antibodies has revealed its involvement in diseases such as hepatocellular carcinoma, breast cancer, and neurological disorders. In cancer biology, CAP2 overexpression has been linked to enhanced tumor invasion and metastasis through actin remodeling mechanisms. Conversely, CAP2 deficiency has been associated with developmental defects in mouse models, particularly in brain and heart tissues. Commercial CAP2 antibodies are typically validated for applications including Western blotting, immunofluorescence, and immunohistochemistry. Recent studies also explore its crosstalk with Wnt and Hippo signaling pathways, though its precise disease mechanisms remain partially controversial, with some reports showing tissue-specific or cancer subtype-dependent expression patterns. These antibodies continue to support ongoing investigations into CAP2's dual functional roles and therapeutic potential.

       
关键字: CAP2抗体;CAP2;CAP2 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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