CDC14A抗体,Rabbit Polyclonal CDC14A Antibody
  • CDC14A抗体,Rabbit Polyclonal CDC14A Antibody
  • CDC14A抗体,Rabbit Polyclonal CDC14A Antibody
  • CDC14A抗体,Rabbit Polyclonal CDC14A Antibody

CDC14A抗体;CDC14A Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
QQ交谈 微信洽谈

产品详情

中文名称:CDC14A抗体英文名称:Rabbit Polyclonal CDC14A Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7021 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CDC14A
2025-05-28 CDC14A抗体 Rabbit Polyclonal CDC14A Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7021 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

Aliasescdc14; hCDC14; DFNB105
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human CDC14A
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13045(CDC14A Antibody) at dilution 1/25. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P13045(CDC14A Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是假设的关于CDC14A抗体的参考文献示例(实际文献需通过学术数据库查询):

1. **"CDC14A phosphatase regulates ciliogenesis through dephosphorylation of TTBK2 kinase"**

*Authors: Yuan et al. (2015)*

**摘要**:研究利用CDC14A特异性抗体,发现其通过去磷酸化TTBK2调控纤毛形成,揭示了CDC14A在精子发生中的关键作用。

2. **"Cell cycle-dependent regulation of DNA damage response by CDC14A"**

*Authors: Smith et al. (2018)*

**摘要**:通过免疫荧光和Western blot(使用CDC14A抗体),证明CDC14A在DNA损伤修复中协调ATR-Chk1信号通路,影响细胞周期检查点。

3. **"CDC14A expression correlates with poor prognosis in colorectal cancer"**

*Authors: Li et al. (2020)*

**摘要**:采用CDC14A抗体进行免疫组化分析,发现其高表达与结直肠癌患者生存率下降相关,提示其作为潜在预后标志物。

4. **"CDC14A knockout mice exhibit neural tube defects via dysregulated Wnt signaling"**

*Authors: Johnson et al. (2019)*

**摘要**:通过抗体检测CDC14A在胚胎发育中的表达,揭示其缺失导致Wnt通路异常,引发神经管闭合缺陷。

*注:以上为假设文献,实际研究请查询PubMed或Web of Science等数据库。*

       

背景信息

The CDC14A antibody is a crucial tool for studying the dual-specificity phosphatase CDC14A, a key regulator of cell cycle progression. CDC14A, part of the conserved CDC14 phosphatase family, plays pivotal roles in mitotic exit, centrosome maturation, and DNA damage response by dephosphorylating cell cycle-related substrates such as CDK1 and certain E3 ubiquitin ligases. It counteracts cyclin-dependent kinase (CDK) activity to ensure orderly transitions between cell cycle phases. Research links CDC14A dysfunction to genomic instability, developmental disorders, and cancers, making it a focus in oncology and cell biology studies.

The CDC14A antibody is widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to detect protein expression, subcellular localization (e.g., nucleolar distribution during interphase), and interaction partners. Its specificity varies across commercial clones, requiring validation via knockout cell lines or siRNA knockdown controls. Studies employing this antibody have revealed CDC14A's context-dependent roles—while essential in some cancers, its loss may paradoxically drive malignancy in others. Recent work also implicates CDC14A in cilia disassembly and neurological development. Researchers prioritize antibodies validated in peer-reviewed publications to ensure reproducibility, particularly given CDC14A's overlapping functions with its paralog CDC14B. Proper controls are critical due to potential cross-reactivity or batch variability.

       
关键字: CDC14A抗体;CDC14A;CDC14A Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

CDC14A抗体;CDC14A Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1800
VIP1年
费雪(杭州)医学研究有限公司
2025-11-03
询价
VIP3年
维百奥(北京)生物科技有限公司
2025-10-27
询价
上海华盈生物医药科技有限公司
2025-11-09
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.