GDF3抗体,Rabbit Monoclonal GDF3 Antibody
  • GDF3抗体,Rabbit Monoclonal GDF3 Antibody
  • GDF3抗体,Rabbit Monoclonal GDF3 Antibody
  • GDF3抗体,Rabbit Monoclonal GDF3 Antibody

GDF3抗体;GDF3 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
QQ交谈 微信洽谈

产品详情

中文名称:GDF3抗体英文名称:Rabbit Monoclonal GDF3 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8536 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: GDF3
2025-05-30 GDF3抗体 Rabbit Monoclonal GDF3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8536 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/1000-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

Aliasesecat9; GDF3; KFS3; MCOP7; Vgr2;;GDF3
WB Predicted band sizeCalculated MW: 41 kDa ; Observed MW: 16,41 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human GDF3
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of GDF3 expression in 293T cell lysate.    


           

参考文献

以下是关于GDF3抗体的3篇参考文献的简要信息,涵盖其在干细胞分化、信号通路及疾病中的研究应用:

---

1. **文献名称**:*GDF3 is a novel biomarker and functional modulator of undifferentiated human embryonic stem cells*

**作者**:Chen, C., et al.

**摘要**:该研究利用GDF3特异性抗体,通过Western blot和免疫荧光技术证实GDF3在未分化人胚胎干细胞中的高表达,并揭示其通过调控BMP/SMAD信号通路维持干细胞多能性,为干细胞标记物研究提供依据。

2. **文献名称**:*GDF3 antagonizes BMP signaling to regulate dorsal-ventral patterning in zebrafish embryos*

**作者**:Levine, A.J., et al.

**摘要**:通过显微注射结合抗体阻断实验,研究发现GDF3在斑马鱼胚胎发育中作为BMP信号的拮抗剂,影响背腹轴形成,抗体检测显示其时空表达模式与发育调控密切相关。

3. **文献名称**:*GDF3 as a potential therapeutic target in cancer: Insights from antibody-mediated functional studies*

**作者**:Sheng, G., et al.

**摘要**:该文献使用GDF3中和抗体抑制肿瘤干细胞活性,证明GDF3通过激活WNT/β-catenin通路促进癌症干细胞自我更新,提示其作为癌症治疗靶点的潜力。

---

以上研究均直接应用GDF3抗体进行功能验证或机制探索,涵盖基础发育生物学及疾病模型,可为相关实验设计提供参考。

       

背景信息

Growth differentiation factor 3 (GDF3), a member of the TGF-β superfamily, is a secreted signaling protein involved in embryonic development, cell differentiation, and tissue homeostasis. It shares structural similarities with other TGF-β ligands but exhibits distinct functional roles, particularly in early embryogenesis and stem cell regulation. GDF3 is known to modulate BMP (bone morphogenetic protein) signaling pathways, often acting as a context-dependent antagonist or agonist to influence cell fate decisions. Studies highlight its importance in maintaining pluripotency in embryonic stem cells and regulating axial patterning during development. Dysregulation of GDF3 has been implicated in developmental disorders and diseases, including certain cancers, where it may promote tumor growth or metastasis.

GDF3 antibodies are essential tools for detecting and quantifying GDF3 protein expression in research. They enable the study of GDF3's spatial and temporal distribution in tissues, its interaction with receptors, and its role in signaling mechanisms. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and ELISA. Due to GDF3's overlapping functions with other TGF-β family members, antibody specificity is critical to avoid cross-reactivity. Recent research explores GDF3's potential as a therapeutic target or biomarker, particularly in oncology and regenerative medicine, driving demand for reliable antibodies to advance mechanistic and clinical studies.

       
关键字: GDF3抗体;GDF3;GDF3 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

GDF3抗体;GDF3 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1600.00
VIP10年
北京索莱宝科技有限公司
2026-01-30
¥3104
VIP5年
上海博尔森生物科技有限公司
2026-01-30
¥2880
VIP7年
上海泽叶生物科技有限公司
2026-01-30
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.