生物活性(-)-α-Pinene是一种单萜类化合物,通过在BZD结合位点作为部分调节剂与GABAA-苯二氮卓(BZD)受体直接结合,显示出增强睡眠的特性。靶点HumanEndogenousMetabolite体外研究(-)-α-pineneenhancesthequantityofnon-rapideyemovementsleep(NREMS)withoutaffectingtheintensityofNREMSbyprolongingGABAergicsynaptictransmission,actingasapartialmodulatorofGABAA-BZDreceptorsanddirectlybindingtotheBZDbindingsiteofGABAAreceptor.
江阴市王馗生物科技有限公司
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