产品概述
Cyclin D1 Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,IP
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
CCND1
CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1
595
P24385
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100 IP: 1:20
Calculated MW: 34 kDa; Observed MW: 34 kDa
研究背景
Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
研究领域
Cell Biology
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