货号:GS40496
Oloctinebart is a humanized monoclonal antibody that specifically targets galectin‑3 (Gal‑3, encoded by the LGALS3 gene), a β‑galactoside‑binding lectin involved in multiple pathological processes. By binding to galectin‑3, oloctinebart blocks its interaction with ligands, thereby inhibiting its pleiotropic functions in inflammation, fibrosis, immune modulation, and tumor progression. It is being developed as a potential therapeutic for galectin‑3‑driven diseases, including fibrotic disorders (e.g., non‑alcoholic steatohepatitis, pulmonary fibrosis), certain cancers, and chronic inflammatory conditions.
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