货号:GS40219
Emapalumab is a human immunoglobulin G1 (IgG1) monoclonal antibody specifically approved for the treatment of primary hemophagocytic lymphohistiocytosis (HLH). It functions as a targeted interferon-gamma (IFN-γ) antagonist. Emapalumab binds with high affinity to free, soluble IFN-γ in the bloodstream, thereby neutralizing this key inflammatory cytokine. This action directly counteracts the life-threatening, hyperinflammatory "cytokine storm" that is the hallmark of HLH, helping to restore immune system balance.
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