货号:GS40615
Robatumumab is a fully human monoclonal antibody targeting insulin-like growth factor-1 receptor (IGF-1R). It blocks IGF-1R activation by IGF-1 and IGF-2, inhibiting downstream signaling pathways involved in cell proliferation, survival, and metastasis. It was investigated for the treatment of solid tumors and sarcomas, particularly Ewing's sarcoma.
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