Anti-IL27 Polyclonal Antibody

IL 27;IL 27 A;IL 27 subunit alpha;IL 27A;IL27;IL27 A;IL27A;IL27p28;IL30;interleukin 27;Interleukin 27 subunit alpha;p28

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).