ANTI-CD86抗体

CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B7), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.                                      

欣博盛生物科技有限公司是一家致力于生命科学和生物技术领域的高科技企业。 公司由在国内科研试剂领域有着十几年从业经验的专业技术团队和企业管理 团队组建而成，专门从事以抗体、细胞因子、免疫检测试剂盒等免疫学产品为主的生物试剂的研发与销售。公司代理40余家欧美著名生物技术公司的相关产品， 能为生命科学多研究领域的广大科研人员提供数万种抗体、数千种蛋白以及相关检测试剂盒等。经过几年的不懈努力，欣博盛生物科技有限公司已成为免疫学、 细胞生物学、分子生物学等领域科研产品的顶尖供应商。同时，公司自主研发的ELISA试剂盒，品质卓越， 行业领先;在国内众多重点实验室广泛使用，深受广 大科研人员的好评。欣博盛品牌ELISA试剂盒自推出以来已先后在Nature, PNAS, Cell research等国际权威杂志文章中被引用。