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ACS Combinatorial Science

ACS Combinatorial Science

IF:3.78
The Journal of Combinatorial Chemistry has been relaunched as ACS Combinatorial Science under the leadership of new Editor-in-Chief M.G. Finn of The Scripps Research Institute. The journal features an expanded scope and will build upon the legacy of the Journal of Combinatorial Chemistry, a highly cited leader in the field.

The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS

Published: 10 October 2022 DOI: 10.1038/s41467-022-33671-5
Tian-Chen Xiong, Ming-Cong Wei, Fang-Xu Li, Miao Shi, Hu Gan, Zhen Tang, Hong-Peng Dong, Tianzi Liuyu, Pu Gao, Bo Zhong, Zhi-Dong Zhang, Dandan Lin

The effect of enantioselective chiral covalent organic frameworks and cysteine sacrificial donors on photocatalytic hydrogen evolution.

Published: 1 October 2022 DOI: 10.1038/s41467-022-33501-8
Weijun Weng, Jia Guo

An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway

Published: 10 March 2022 DOI: 10.1038/s41467-022-28946-w
Fuhui Meng, Yang Xiao, Yujia Ji, Ziyi Sun, Xiaoming Zhou

The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery

Published: 20 January 2021 DOI: 10.1038/s41467-020-20718-8
Ziyang Fu, Bin Huang, Jinle Tang, Shuyan Liu, Ming Liu, Yuxin Ye, Zhihong Liu, Yuxian Xiong, Wenning Zhu, Dan Cao, Jihui Li, Xiaogang Niu, Huan Zhou, Yong Juan Zhao, Guoliang Zhang, Hao Huang

Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia

Published: 4 January 2021 DOI: 10.1038/s41467-020-20259-0
Hu Lei, Han-Zhang Xu, Hui-Zhuang Shan, Meng Liu, Ying Lu, Zhi-Xiao Fang, Jin Jin, Bo Jing, Xin-Hua Xiao, Shen-Meng Gao, Feng-Hou Gao, Li Xia, Li Yang, Li-Gen Liu, Wei-Wei Wang, Chuan-Xu Liu, Yin Tong, Yun-Zhao Wu, Jun-Ke Zheng, Guo-Qiang Chen, Li Zhou, Ying-Li Wu

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model

Published: 12 November 2020 DOI: 10.1038/s41467-020-19547-6
Xufeng Cen, Yanying Chen, Xiaoyan Xu, Ronghai Wu, Fusheng He, Qingwei Zhao, Qiming Sun, Cong Yi, Jie Wu, Ayaz Najafov, Hongguang Xia

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

Published: 4 September 2020 DOI: 10.1038/s41467-020-18233-x
Lifeng Fu, Fei Ye, Yong Feng, Feng Yu, Qisheng Wang, Yan Wu, Cheng Zhao, Huan Sun, Baoying Huang, Peihua Niu, Hao Song, Yi Shi, Xuebing Li, Wenjie Tan, Jianxun Qi, George Fu Gao

Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response

Published: 7 March 2019 DOI: 10.1016/j.molcel.2018.12.006
Johannes H Wilbertz, Franka Voigt, Ivana Horvathova, Gregory Roth, Yinxiu Zhan, Jeffrey A Chao

Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

Published: 30 April 2018 DOI: 10.1038/s41467-018-04072-4
Dingfeng Li, Juan Zhang, Ming Wang, Xiaohui Li, Huarui Gong, Huiping Tang, Lin Chen, Lili Wan, Qiang Liu

Selective isolation of gold facilitated by second-sphere coordination with α-cyclodextrin.

Published: 1 January 2013 DOI: 10.1038/ncomms2891
Zhichang Liu, Marco Frasconi, Juying Lei, Zachary J Brown, Zhixue Zhu, Dennis Cao, Julien Iehl, Guoliang Liu, Albert C Fahrenbach, Youssry Y Botros, Omar K Farha, Joseph T Hupp, Chad A Mirkin, J Fraser Stoddart