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Biomolecules

IF:4.8 CiteScore:9.4 Articles:1640

Biomolecules (ISSN 2218-273X) is an international, peer-reviewed open access journal focusing on biogenic substances and their biological functions, structures, interactions with other molecules, and their microenvironment as well as biological systems. Biomolecules publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.

Oleuropein Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice by Targeting TGF-β1 Signaling Pathway

Published: 22 August 2025 DOI: 10.3390/biom15091211
Liang Zhang, Zhigang Liu, Yayue Hu, Xueze Liu, Zhongyi Yang, Yuming Liu, Ran Jiao, Xiaoting Gu, Weidong Zhang, Xiaohe Li, Honggang Zhou

Brusatol Inhibits Esophageal Squamous Cell Carcinoma Tumorigenesis Through Bad-Mediated Mitochondrial Apoptosis Induction and Anti-Metastasis by Targeting Akt1

Published: 4 June 2025 DOI: 10.3390/biom15060812
Yao Ji, Xinxin Zhu, Yi Shi, Rui Fang, Yimeng Sun, Yurong Ruan, Liying Zhou, Yuanyuan Ge, Qichao Luo, Junyan Zhang, Junting Ma

LIFR-Mediated ERBB2 Signaling Is Essential for Successful Embryo Implantation in Mice

Published: 10 May 2025 DOI: 10.3390/biom15050698
Jumpei Terakawa, Sakura Nakamura, Mana Ohtomo, Saki Uehara, Yui Kawata, Shunsuke Takarabe, Hibiki Sugita, Takafumi Namiki, Atsuko Kageyama, Michiko Noguchi, Hironobu Murakami, Naomi Kashiwazaki, Junya Ito

Iberverin Downregulates GPX4 and SLC7A11 to Induce Ferroptotic Cell Death in Hepatocellular Carcinoma Cells

Published: 5 November 2024 DOI: 10.3390/biom14111407
Haoying Yang, Bolei Dai, Liangjie Chen, Yingping Li, Xiaorui Jin, Chengchang Gao, Linfen Han, Xueli Bian

Identification of TAT as a Biomarker Involved in Cell Cycle and DNA Repair in Breast Cancer

Published: 30 August 2024 DOI:
Fei Xie, Saiwei Hua, Yajuan Guo, Taoyuan Wang, Changliang Shan, Lianwen Zhang, Tao He

Revealing the Mechanism of Esculin in Treating Renal Cell Carcinoma Based on Network Pharmacology and Experimental Validation

Published: 22 August 2024 DOI: 10.3390/biom14081043
Zixuan Chen, Cunzhou Wang, Yuesong Cai, An Xu, Chengtao Han, Yanjun Tong, Sheng Cheng, Min Liu

Pregnancy-Specific Beta-1-Glycoprotein 1 Increases HTR-8/SVneo Cell Migration through the Orai1/Akt Signaling Pathway

Published: 29 February 2024 DOI: 10.3390/biom14030293
Qunhua Wang, Yan Fang, Yuan Li, Huali Liu, Maoni Zhu, Xue Hu, Jinzhuo Zhou, Anqi Deng, Bing Shen, Hongbo Chen

Corticosterone Impairs Hippocampal Neurogenesis and Behaviors through p21-Mediated ROS Accumulation

Published: 23 February 2024 DOI: 10.3390/biom14030268
Guanhao Wang, Lining Cao, Shuanqing Li, Meihui Zhang, Yingqi Li, Jinjin Duan, You Li, Zhangsen Hu, Jiaan Wu, Tianming Li, Ming Jiang, Jianfeng Lu

Repurposing an Antioxidant to Kill Mycobacterium tuberculosis by Targeting the 50S Subunit of the Ribosome

Published: 14 December 2023 DOI: 10.3390/biom13121793
Wenqi Dong, Gaoyan Wang, Yajuan Bai, Yuxin Li, Liying Zhao, Wenjia Lu, Chenchen Wang, Zhaoran Zhang, Hao Lu, Xiangru Wang, Huanchun Chen, Chen Tan

Efficacy of HDAC Inhibitors in Driving Peroxisomal β-Oxidation and Immune Responses in Human Macrophages: Implications for Neuroinflammatory Disorders

Published: 23 November 2023 DOI: 10.3390/biom13121696
Andrea Villoria-González, Bettina Zierfuss, Patricia Parzer, Elisabeth Heuböck, Violetta Zujovic, Petra Waidhofer-Söllner, Markus Ponleitner, Paulus Rommer, Jens Göpfert, Sonja Forss-Petter, Johannes Berger, Isabelle Weinhofer

cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels

Published: 24 September 2023 DOI: 10.3390/biom13101438
Ee Chee Ren, Nicole Ziyi Zhuo, Zhi Yi Goh, Isabelle Bonne, Benoît Malleret, Hui Ling Ko

Recent Advances in Peptidoglycan Synthesis and Regulation in Bacteria.

Published: 22 April 2023 DOI: 10.3390/biom13050720
Anne Galinier, Clémentine Delan-Forino, Elodie Foulquier, Hakima Lakhal, Frédérique Pompeo

Efavirenz: History, Development and Future.

Published: 31 December 2022 DOI: 10.3390/biom13010088
Bárbara Costa, Nuno Vale

IL-18BP Improves Early Graft Function and Survival in Lewis–Brown Norway Rat Orthotopic Liver Transplantation Model

Published: 1 December 2022 DOI: 10.3390/biom12121801
Qiang Meng, Weikang Wu, Wenjie Zhang, Juzheng Yuan, Long Yang, Xuan Zhang, Kaishan Tao

Prognostic Impacts of LL-37 in Relation to Lipid Profiles of Patients with Myocardial Infarction: A Prospective Cohort Study.

Published: 14 October 2022 DOI: 10.3390/biom12101482
Runzhen Chen, Hanjun Zhao, Jinying Zhou, Ying Wang, Jiannan Li, Xiaoxiao Zhao, Nan Li, Chen Liu, Peng Zhou, Yi Chen, Li Song, Hongbing Yan

NP-Scout: Machine Learning Approach for the Quantification and Visualization of the Natural Product-Likeness of Small Molecules

Published: 24 January 2019 DOI: 10.3390/biom9020043
Ya Chen, Conrad Stork, Steffen Hirte, Johannes Kirchmair