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Cancers

IF:4.4 CiteScore:8 Articles:5371

Cancers (ISSN 2072-6694) is an international, peer-reviewed open access journal on oncology. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.

Epithelial-Mesenchymal Transition Activates YAP to Drive Malignant Progression and Immune Evasion

Published: 25 August 2025 DOI: 10.3390/cancers17172767
Xi Huang, Mingyan Zhang, Alexander D Pearce, Matthew D Gibbons, Dan Jin, Lu Li, Dongxin Hu, Renbin Liu, Mu Yu, Ming Tan, Jia Chang, Jixin Dong, Mingyi Xie, Weizhou Zhang, Lizi Wu, Catherine Flores, Jörg Bungert, Todd M Brusko, Jianrong Lu

Targeting Hepatocellular Carcinoma Growth: Haprolid’s Inhibition of AKT Signaling Through DExH-Box Helicase 9 Downregulation

Published: 28 January 2025 DOI: 10.3390/cancers17030443
Jun Xing, Xiaoxi Feng, Rutong Zhang, Kaiguang Zhang

LncRNA LOC730101 Promotes Darolutamide Resistance in Prostate Cancer by Suppressing miR-1-3p

Published: 20 July 2024 DOI: 10.3390/cancers16142594
Tianyi Zhou, Steven Nguyen, Jacky Wu, Bin He, Qin Feng

N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents

Published: 27 May 2024 DOI: 10.3390/cancers16112033
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, Yu-Chieh Su, Ming-Hua Shiao, Gary A Piazza, Ashraf H Abadi, Matthias Engel, Mohammad Abdel-Halim

Vascular Immune Evasion of Mesenchymal Glioblastoma Is Mediated by Interaction and Regulation of VE-Cadherin on PD-L1

Published: 25 August 2023 DOI: 10.3390/cancers15174257
Jing Luo, Ziyi Wang, Xuemei Zhang, Haihui Yu, Hui Chen, Kun Song, Yang Zhang, Lawrence M Schwartz, Hongzhuan Chen, Yingbin Liu, Rong Shao

IGF1R Contributes to Cell Proliferation in ALK -Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway

Published: 25 August 2023 DOI: 10.3390/cancers15174252
Jikui Guan, Marcus Borenäs, Junfeng Xiong, Wei-Yun Lai, Ruth H Palmer, Bengt Hallberg

The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells

Published: 29 July 2023 DOI: 10.3390/cancers15153866
Keli Lima, Lívia Bassani Lins de Miranda, Anali Del Milagro Bernabe Garnique, Bruna Oliveira de Almeida, Mariane Cristina do Nascimento, Guilherme Augusto Sousa Alcântara, Glaucia Maria Machado-Santelli, Eduardo Magalhães Rego, João Agostinho Machado-Neto

TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer

Published: 13 April 2023 DOI: 10.3390/cancers15082286
Zhiwei Wu, Changwei Lin, Fan Zhang, Zhixing Lu, Yaohui Wang, Yang Liu, Zhijiao Zhou, Liang Li, Liying Song

Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition

Published: 7 February 2023 DOI: 10.3390/cancers15041044
Saiful Islam, Muhammed H Rahaman, Mingfeng Yu, Benjamin Noll, Jennifer H Martin, Shudong Wang, Richard Head

Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer

Published: 25 January 2023 DOI: 10.3390/cancers15030744
Zijia Huang, Sheng Zhu, Ziqin Han, Chen Li, Junze Liang, Yang Wang, Shuixing Zhang, Jing Zhang

Integrated Analysis and Identification of Critical RNA-Binding Proteins in Bladder Cancer

Published: 31 July 2022 DOI: 10.3390/cancers14153739
Lijiang Gu, Yuhang Chen, Xing Li, Yibo Mei, Jinlai Zhou, Jianbin Ma, Mengzhao Zhang, Tao Hou, Dalin He, Jin Zeng

Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells

Published: 1 April 2022 DOI:
Lei Chen, Yang Yan, Fangen Kong, Jikai Wang, J. Zeng, Zhen Fang, Zheyan Wang, Zhigang Liu, Feifan Liu

Highly Expressed Progesterone Receptor B Isoform Increases Platinum Sensitivity and Survival of Ovarian High-Grade Serous Carcinoma

Published: 8 November 2021 DOI: 10.3390/cancers13215578
Hao Lin, Kuo-Chung Lan, Yu-Che Ou, Chen-Hsuan Wu, Hong-Yo Kang, I-Chieh Chuang, Hung-Chun Fu

LncRNA LINC00518 Acts as an Oncogene in Uveal Melanoma by Regulating an RNA-Based Network

Published: 21 December 2020 DOI: 10.3390/cancers12123867
Cristina Barbagallo, Rosario Caltabiano, Giuseppe Broggi, Andrea Russo, Lidia Puzzo, Teresio Avitabile, Antonio Longo, Michele Reibaldi, Davide Barbagallo, Cinzia Di Pietro, Michele Purrello, Marco Ragusa

C20orf27 Promotes Cell Growth and Proliferation of Colorectal Cancer via the TGFβR-TAK1-NF?B Pathway

Published: 2 February 2020 DOI: 10.3390/cancers12020336
Jing Gao, Yang Wang, Weixia Zhang, Jing Zhang, Shaohua Lu, Kun Meng, Xingfeng Yin, Zhenghua Sun, Qing-Yu He

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

Published: 13 January 2020 DOI: 10.3390/cancers12010193
Jin-Feng Teng, Qi-Bing Mei, Xiao-Gang Zhou, Yong Tang, Rui Xiong, Wen-Qiao Qiu, Rong Pan, Betty Yuen-Kwan Law, Vincent Kam-Wai Wong, Chong-Lin Yu, Han-An Long, Xiu-Li Xiao, Feng Zhang, Jian-Ming Wu, Da-Lian Qin, An-Guo Wu