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Cell Research
Cell Research
IF:25.9
CiteScore:53.9
Articles:2420
Cell Research (CR) is an international journal published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS). It focuses on publishing original research articles and reviews in various areas of life sciences, particularly those related to molecular and cell biology. The journal covers a broad range of topics including cell growth, differentiation, and apoptosis; signal transduction; stem cell biology and development; chromatin, epigenetics, and transcription; RNA biology; structural and molecular biology; cancer biology and metabolism; immunity and molecular pathogenesis; molecular and cellular neuroscience; plant molecular and cell biology; and omics, system biology, and synthetic biology. CR is recognized as China's best international journal in life sciences and is part of Springer Nature's prestigious family of Molecular Cell Biology journals.
LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer
Published: 2 January 2025
DOI: 10.1038/s41422-024-01025-z
Fei Li, Pengfei Dai, Huili Shi, Yajuan Zhang, Juan He, Anuradha Gopalan, Dan Li, Yu Chen, Yarui Du, Guoliang Xu, Weiwei Yang, Chao Liang, Dong Gao
Fei Li, Pengfei Dai, Huili Shi, Yajuan Zhang, Juan He, Anuradha Gopalan, Dan Li, Yu Chen, Yarui Du, Guoliang Xu, Weiwei Yang, Chao Liang, Dong Gao
Cryo-EM structures of human organic anion transporting polypeptide OATP1B1
Published: 6 September 2023
DOI: 10.1038/s41422-023-00870-8
Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang
Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Published: 17 July 2023
DOI: 10.1038/s41422-023-00848-6
Yuan-li Ai, Wei-jia Wang, Fan-jian Liu, Wei Fang, Hang-zi Chen, Liu-zheng Wu, Xuehui Hong, Yuekun Zhu, Ci-xiong Zhang, Long-yu Liu, Wen-bin Hong, Bo Zhou, Qi-tao Chen, Qiao Wu
Yuan-li Ai, Wei-jia Wang, Fan-jian Liu, Wei Fang, Hang-zi Chen, Liu-zheng Wu, Xuehui Hong, Yuekun Zhu, Ci-xiong Zhang, Long-yu Liu, Wen-bin Hong, Bo Zhou, Qi-tao Chen, Qiao Wu
Structural basis of signaling regulation of the human melanocortin-2 receptor by MRAP1
Published: 2 January 2023
DOI: 10.1038/s41422-022-00751-6
Ping Luo, Wenbo Feng, Shanshan Ma, Antao Dai, Kai Wu, Xianyue Chen, Qingning Yuan, Xiaoqing Cai, Dehua Yang, Ming-Wei Wang, H. Eric Xu, Yi Jiang
Ping Luo, Wenbo Feng, Shanshan Ma, Antao Dai, Kai Wu, Xianyue Chen, Qingning Yuan, Xiaoqing Cai, Dehua Yang, Ming-Wei Wang, H. Eric Xu, Yi Jiang
Structural insights into ligand binding and activation of the human thyrotropin-releasing hormone receptor
Published: 1 April 2022
DOI: 10.1038/s41422-022-00641-x
Youwei Xu, Hongmin Cai, Chongzhao You, Xinheng He, Qingning Yuan, Hualiang Jiang, Xi Cheng, Yi Jiang, H. Eric Xu
Youwei Xu, Hongmin Cai, Chongzhao You, Xinheng He, Qingning Yuan, Hualiang Jiang, Xi Cheng, Yi Jiang, H. Eric Xu
The structure of erastin-bound xCT–4F2hc complex?reveals molecular mechanisms underlying erastin-induced ferroptosis
Published: 29 March 2022
DOI: 10.1038/s41422-022-00642-w
Renhong Yan, Enjun Xie, Yaning Li, Jin Li, Yuanyuan Zhang, Ximin Chi, Xueping Hu, Lei Xu, Tingjun Hou, Brent R. Stockwell, Junxia Min, Qiang Zhou, Fudi Wang
Renhong Yan, Enjun Xie, Yaning Li, Jin Li, Yuanyuan Zhang, Ximin Chi, Xueping Hu, Lei Xu, Tingjun Hou, Brent R. Stockwell, Junxia Min, Qiang Zhou, Fudi Wang
Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate
Published: 4 February 2022
DOI: 10.1038/s41422-022-00622-0
Ao Hu, Jing-Zan Zhang, Jie Wang, Chen-Chen Li, Meng Yuan, Gang Deng, Zi-Cun Lin, Zhi-Ping Qiu, Hu-Yue Liu, Xian-Wei Wang, Peng-Cheng Wei, Xiao He, Xiaolu Zhao, Wen-Wei Qiu, Bao-Liang Song
Ao Hu, Jing-Zan Zhang, Jie Wang, Chen-Chen Li, Meng Yuan, Gang Deng, Zi-Cun Lin, Zhi-Ping Qiu, Hu-Yue Liu, Xian-Wei Wang, Peng-Cheng Wei, Xiao He, Xiaolu Zhao, Wen-Wei Qiu, Bao-Liang Song
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor
Published: 25 November 2020
DOI: 10.1038/s41422-020-00442-0
Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M. Rosenkilde, H. Eric Xu, Yan Zhang, Ming-Wei Wang
Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M. Rosenkilde, H. Eric Xu, Yan Zhang, Ming-Wei Wang
Molecular basis for ligand activation of the human KCNQ2 channel
Published: 3 September 2020
DOI: 10.1038/s41422-020-00410-8
Xiaoxiao Li, Qiansen Zhang, Peipei Guo, Jie Fu, Lianghe Mei, Dashuai Lv, Jiangqin Wang, Dongwu Lai, Sheng Ye, Huaiyu Yang, Jiangtao Guo
Xiaoxiao Li, Qiansen Zhang, Peipei Guo, Jie Fu, Lianghe Mei, Dashuai Lv, Jiangqin Wang, Dongwu Lai, Sheng Ye, Huaiyu Yang, Jiangtao Guo
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy.
Published: 24 August 2020
DOI:
Mengze Lv, Meixia Chen, Rui Zhang, Wen Zhang, Chenguang Wang, Yan Zhang, Xiaoming Wei, Yukun Guan, Jiejie Liu, Kaichao Feng, Miao Jing, Xurui Wang, Yun-Cai Liu, Qian Mei, Weidong Han, Zhengfan Jiang
Mengze Lv, Meixia Chen, Rui Zhang, Wen Zhang, Chenguang Wang, Yan Zhang, Xiaoming Wei, Yukun Guan, Jiejie Liu, Kaichao Feng, Miao Jing, Xurui Wang, Yun-Cai Liu, Qian Mei, Weidong Han, Zhengfan Jiang
Elimination of senescent cells by ?-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice.
Published: 27 April 2020
DOI: 10.1038/s41422-020-0314-9
Yusheng Cai, Huanhuan Zhou, Yinhua Zhu, Qi Sun, Yin Ji, Anqi Xue, Yuting Wang, Wenhan Chen, Xiaojie Yu, Longteng Wang, Han Chen, Cheng Li, Tuoping Luo, Hongkui Deng
Yusheng Cai, Huanhuan Zhou, Yinhua Zhu, Qi Sun, Yin Ji, Anqi Xue, Yuting Wang, Wenhan Chen, Xiaojie Yu, Longteng Wang, Han Chen, Cheng Li, Tuoping Luo, Hongkui Deng
A complex structure of arrestin-2 bound to a G protein-coupled receptor
Published: 27 November 2019
DOI: 10.1038/s41422-019-0256-2
Wanchao Yin, Zhihai Li, Mingliang Jin, Yu-Ling Yin, Parker W. de Waal, Kuntal Pal, Yanting Yin, Xiang Gao, Yuanzheng He, Jing Gao, Xiaoxi Wang, Yan Zhang, Hu Zhou, Karsten Melcher, Yi Jiang, Yao Cong, X. Edward Zhou, Xuekui Yu, H. Eric Xu
Wanchao Yin, Zhihai Li, Mingliang Jin, Yu-Ling Yin, Parker W. de Waal, Kuntal Pal, Yanting Yin, Xiang Gao, Yuanzheng He, Jing Gao, Xiaoxi Wang, Yan Zhang, Hu Zhou, Karsten Melcher, Yi Jiang, Yao Cong, X. Edward Zhou, Xuekui Yu, H. Eric Xu
Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D
Published: 16 October 2019
DOI: 10.1038/s41422-019-0244-6
Jianxu Li, Fang Yu, Hui Guo, Renxue Xiong, Wenjing Zhang, Fangyuan He, Minhua Zhang, Peng Zhang
Jianxu Li, Fang Yu, Hui Guo, Renxue Xiong, Wenjing Zhang, Fangyuan He, Minhua Zhang, Peng Zhang
Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition.
Published: 9 September 2019
DOI: 10.1038/s41422-019-0229-5
Wencao Zhao, Le Cao, Hanru Ying, Wenjuan Zhang, Dantong Li, Xiaolong Zhu, Wenzhi Xue, Shuang Wu, Mengye Cao, Cong Fu, Haonan Qi, Yimei Hao, Yun-Chi Tang, Jun Qin, Tao P. Zhong, Xiaoxi Lin, Luyang Yu, Xuri Li, Lin Li, Dianqing Wu, Weijun Pan
Wencao Zhao, Le Cao, Hanru Ying, Wenjuan Zhang, Dantong Li, Xiaolong Zhu, Wenzhi Xue, Shuang Wu, Mengye Cao, Cong Fu, Haonan Qi, Yimei Hao, Yun-Chi Tang, Jun Qin, Tao P. Zhong, Xiaoxi Lin, Luyang Yu, Xuri Li, Lin Li, Dianqing Wu, Weijun Pan
Maternal exposure to triclosan constitutes a yet unrecognized risk factor for autism spectrum disorders
Published: 28 August 2019
DOI: 10.1038/s41422-019-0220-1
Zijian Hao, Qionghui Wu, Zhengwei Li, Yali Li, Qiu Li, Xi Lai, Huan Liu, Menghuan Zhang, Ting Yang, Jie Chen, Yaping Tang, Jingkun Miao, Huatai Xu, Tingyu Li, Ronggui Hu
Zijian Hao, Qionghui Wu, Zhengwei Li, Yali Li, Qiu Li, Xi Lai, Huan Liu, Menghuan Zhang, Ting Yang, Jie Chen, Yaping Tang, Jingkun Miao, Huatai Xu, Tingyu Li, Ronggui Hu
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts
Published: 3 July 2019
DOI:
Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui LYU, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, Kuanhui Xiang, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi, Shichun Lu, Hongkui Deng
Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui LYU, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, Kuanhui Xiang, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi, Shichun Lu, Hongkui Deng
Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens
Published: 25 October 2018
DOI: 10.1038/s41422-018-0103-x
Gong-Bo Fu, Wei-Jian Huang, Min Zeng, Xu Zhou, Hong-Ping Wu, Chang-Cheng Liu, Han Wu, Jun Weng, Hong-Dan Zhang, Yong-Chao Cai, Charles Ashton, Min Ding, Dan Tang, Bao-Hua Zhang, Yi Gao, Wei-Feng Yu, Bo Zhai, Zhi-Ying He, Hong-Yang Wang, He-Xin Yan
Gong-Bo Fu, Wei-Jian Huang, Min Zeng, Xu Zhou, Hong-Ping Wu, Chang-Cheng Liu, Han Wu, Jun Weng, Hong-Dan Zhang, Yong-Chao Cai, Charles Ashton, Min Ding, Dan Tang, Bao-Hua Zhang, Yi Gao, Wei-Feng Yu, Bo Zhai, Zhi-Ying He, Hong-Yang Wang, He-Xin Yan