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Cellular signalling

IF:4.4 CiteScore:8.4 Articles:250

Cellular Signalling publishes original research describing fundamental and clinical findings on the mechanisms, actions and structural components of cellular signalling systems in vitro and in vivo. Cellular Signalling aims at full length research papers defining signalling systems ranging from microorganisms to cells, tissues and higher organisms.

SERPINH1 promotes malignant progression of laryngeal squamous cell carcinoma via COL7A1-mediated Wnt/β-catenin signaling

Published: 31 July 2025 DOI: 10.1016/j.cellsig.2025.112043
Feinan He, Jinqiu Li, Weifang Tong, Sanchun Wang, Hongyan Wang, Baishuo Huang, Bo Teng

Chemerin-stimulated HSP90AB1 SUMOylation promotes monocyte activation and ERK1/2 phosphorylation via β2 integrin

Published: 29 July 2025 DOI: 10.1016/j.cellsig.2025.112036
Lili Wu , Guona Chen , Fan Wu , Qiongyu Lu , Lijie Ren , Chaojun Tang , Shouming Zhao , Fengchan Li

SCARA5 deficiency inhibits ferroptosis via regulating iron homeostasis and results in sorafenib resistance in hepatocellular carcinoma

Published: 13 February 2025 DOI: 10.1016/j.cellsig.2025.111656
Cong Chen , Lan Wang , Xiao-Fang Cui, Xu-Yang Shang, Shi-Hao Bai, Lin Li, Na Wang, Ze-Guang Han

Identification of PLAC1 as a prognostic biomarker and molecular target in clear cell renal cell carcinoma

Published: 13 January 2025 DOI: 10.1016/j.cellsig.2025.111606
Ying Kong , Zongming Jia , Yizhang Sun , Lichen Jin , Tong Zhang , Qiya Xu , Yuhua Huang

HDAC inhibitor enhances ferroptosis susceptibility of AML cells by stimulating iron metabolism

Published: 3 January 2025 DOI: 10.1016/j.cellsig.2024.111583
Ruipeng Bian , Yingying Shang , Nahua Xu , Baiping Liu , Yanni Ma , Hui Li , Jieping Chen , Qi Yao

SGK1 mediates herpes simplex keratitis via the PI3K/SGK1/Wnt signaling pathways

Published: 12 December 2024 DOI: 10.1016/j.cellsig.2024.111566
Wei Ye, Songyi Tang, Yue Wang, Wenzhe Wang, Yumeilan Liu, Huanhuan Xu, Hu Meng, Yan Lu, Zhenping Huang, Yirui Ge

SSBP1 positively regulates RRM2, affecting epithelial mesenchymal transition and cell cycle arrest in human lung adenocarcinoma cells

Published: 4 December 2024 DOI: 10.1016/j.cellsig.2024.111552
Xingyu Yang, Bingfeng Ma, Yafeng Liu, Jiawei Zhou, Jianqiang Guo, Yuanyuan Peng, Ying Bai, Jing Wu, Dong Hu

ACVR1 mediates renal tubular EMT in kidney fibrosis via AKT activation

Published: 23 November 2024 DOI: 10.1016/j.cellsig.2024.111521
Tianli Yu, Zhangyu Mai, Lingyun Zheng

Inhibitory effects of circR-127aa on gastric cancer progression and tumor growth

Published: 22 November 2024 DOI: 10.1016/j.cellsig.2024.111520
Lei Qiao, Wen Pan, Yi Ba

ARL8B promotes hepatocellular carcinoma progression and inhibits antitumor activity of lenvatinib via MAPK/ERK signaling by interacting with RAB2A

Published: 15 October 2024 DOI: 10.1016/j.cellsig.2024.111470
Mo-Mo Cao , Yi-Ming Li , Xiang Ding , Feng Fang , Lian-Yue Yang

Bmal1 upregulates ATG5 expression to promote autophagy in skin cutaneous melanoma.

Published: 27 September 2024 DOI: 10.1016/j.cellsig.2024.111439
Tao Lei , Xin Cai , Hao Zhang , Xunping Wu , Zhimin Cao , Wen Li , Xingming Xie , Bangyan Zhang

ESRRA modulation by empagliflozin mitigates diabetic tubular injury via mitochondrial restoration

Published: 24 July 2024 DOI: 10.1016/j.cellsig.2024.111308
Keju Yang , Wei Liang , Hongtu Hu , Zongwei Zhang , Yiqun Hao , Zhixia Song , Lin Yang , Jijia Hu , Zhaowei Chen , Guohua Ding

microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.

Published: 11 March 2024 DOI: 10.1016/j.cellsig.2024.111136
Xin Chen , Yanhong Cao , Yining Guo , Jing Liu , Xiaohan Ye , Huan Li , Lu Zhang , Wenwei Feng , Shaoxiang Xian , Zhongqi Yang , Lingjun Wang , Ting Wang

Phosphorylated Hsp27 promotes adriamycin resistance in breast cancer cells through regulating dual phosphorylation of c-Myc

Published: 4 October 2023 DOI: 10.1016/j.cellsig.2023.110913
Xiaowen Bi , Miao Zhang , Jinyi Zhou , Xintong Yan , Lixia Cheng , Lan Luo , Chunhong Huang , Zhimin Yin

UHRF2 promotes the malignancy of hepatocellular carcinoma by PARP1 mediated autophagy

Published: 1 September 2023 DOI:
Yiqi Zhang , Kejia Wu , Yuxin Liu , Shuangling Sun , Yue Shao , Qingxiu Li , Xinying Sui , Changzhu Duan

Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats

Published: 1 August 2023 DOI: 10.1016/j.cellsig.2023.110732
Yanyun Zhao , Sihan Huang , Renwei Xie , Jun Liu

The oncogenic role of TFAP2A in bladder urothelial carcinoma via a novel long noncoding RNA TPRG1-AS1/DNMT3A/CRTAC1 axis

Published: 1 February 2023 DOI: 10.1016/j.cellsig.2022.110527
Jiani He , Changming Dong , Hao Zhang , Yuanjun Jiang , Tao Liu , Xiaojun Man

Complement factor D derived from epicardial adipose tissue participates in cardiomyocyte apoptosis after myocardial infarction by mediating PARP-1 activity.

Published: 1 January 2023 DOI: 10.1016/j.cellsig.2022.110518
Shuang Hao, Jingchao Zhang, Yu Pei, Longhui Guo, Zhenxing Liang

Early growth response genes 2 and 3 induced by AP-1 and NF-κB modulate TGF-β1 transcription in NK1.1? CD4+ NKG2D+ T cells

Published: 1 December 2020 DOI: 10.1016/j.cellsig.2020.109800
Sen Han , Tao Zhu , Shizhen Ding , Jianqiang Wen , Zhijie Lin , Guotao Lu , Yu Zhang , Weiming Xiao , Yanbing Ding , Xiaoqin Jia , Huabiao Chen , Weijuan Gong