MedComm - chemicalbook

Outer membrane vesicle contributes to the Pseudomonas aeruginosa resistance to antimicrobial peptides in the acidic airway of bronchiectasis patients

Published: 30 January 2025 DOI: 10.1002/mco2.70084
Yingzhou Xie, Yi-Han Shi, Le-Le Wang, Cheng-Wei Li, Min Wu, Jin-Fu Xu

Salt‐inducible kinase 2 confers radioresistance in colorectal cancer by facilitating homologous recombination repair

Published: 28 January 2025 DOI: 10.1002/mco2.70083
Yuan Meng, Shuo Li, Da-Shan Lu, Xue Chen, Lu Li, You-fa Duan, Gao-yuan Wang, Wenlin Huang, Ran-yi Liu

Inhibition of Selenoprotein I promotes ferroptosis and reverses resistance to platinum chemotherapy by impairing Akt phosphorylation in ovarian cancer

Published: 11 December 2024 DOI: 10.1002/mco2.70033
Jing Li, Mimi Chen, Dingwen Huang, Ziyin Li, Yu Chen, Jinhua Huang, Yuanqun Chen, Zhili Zhou, Zhiying Yu

Nicotinamide mononucleotide protects STAT1 from oxidative stress‐induced degradation to prevent colorectal tumorigenesis

Published: 21 November 2024 DOI: 10.1002/mco2.70006
Ting Li, Chengting Luo, Zongyuan Liu, Jinyu Li, Meng Han, Ran Zhang, Yuling Chen, Haiteng Deng

Autophagy-mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularization

Published: 29 July 2024 DOI:
Xianyang Liu, Qian Zhou, Jiayu Meng, Hangjia Zuo, Ruonan Li, Rui Zhang, Huiping Lu, Zhi Zhang, Hongshun Li, Shuhao Zeng, Meng Tian, Hong Wang, Ke Hu, Na Li, Liming Mao, Shengping Hou

iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation

Published: 9 May 2024 DOI:
Yuxuan Zhang, Qingxin Shi, Peiyun Wang, Chujun Huang, Shuqing Tang, Miaojin Zhou, Qian Hu, Lingqian Wu, Desheng Liang

Maresin-1 ameliorates hypertensive vascular remodeling through its receptor LGR6

Published: 9 March 2024 DOI:
Zheng Yin, Jishou Zhang, Mengmeng Zhao, Shanshan Peng, Jing Ye, Jianfang Liu, Yao Xu, Shuwan Xu, Wei Pan, Cheng Wei, Juan-Juan Qin, Jun Wan, Menglong Wang

Arachidonic acid metabolism in health and disease

Published: 20 September 2023 DOI: 10.1002/mco2.363
Yiran Zhang, Yingxiang Liu, Jin Sun, Wei Zhang, Zheng Guo, Qiong Ma

Cellular senescence primes liver fibrosis regression through Notch-EZH2

Published: 21 August 2023 DOI: 10.1002/mco2.346
Ping Song, Juan-Li Duan, Jian Ding, Jing-Jing Liu, Zhi-Qiang Fang, Hao Xu, Zhi-Wen Li, Wei Du, Ming Xu, Yu-Wei Ling, Fei He, Kai-Shan Tao, Lin Wang

Phosphatidylserine decarboxylase downregulation in uric acid?induced hepatic mitochondrial dysfunction and apoptosis

Published: 26 July 2023 DOI: 10.1002/mco2.336
Ning Liu, Lei Huang, Hu Xu, Xinyu He, Xueqing He, Jun Cao, Wenjun Xu, Yaoxing Wang, Hongquan Wei, Sheng Wang, Hong Zheng, Shan Gao, Youzhi Xu, Wenjie Lu

The ubiquitin-specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression

Published: 22 July 2023 DOI:
Bokang Yan, Jiaxing Guo, Zuli Wang, Jieling Ning, Haiyan Wang, Long Shu, Kuan Hu, Ling Chen, Ying Shi, Lingqiang Zhang, Shuang Liu, Yongguang Tao, Desheng Xiao

Tyrosine phosphatase SHP2 exacerbates psoriasis-like skin inflammation in mice via ERK5-dependent NETosis.

Published: 4 March 2022 DOI: 10.1002/mco2.120
Yan Ding, Zijun Ouyang, Chenyang Zhang, Yuyu Zhu, Qiang Xu, Haiyan Sun, Jiao Qu, Yang Sun