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Nature

IF:50.5 CiteScore:90 Articles:3652

Nature is a prestigious international journal that publishes peer-reviewed research in various scientific and technological fields. The selection of articles is based on criteria such as originality, importance, interdisciplinary relevance, timeliness, accessibility, elegance, and surprising conclusions. In addition to showcasing significant scientific advances, Nature delivers rapid, authoritative, insightful news, and interpretation of current and upcoming trends impacting science, scientists, and the broader public. The journal serves a dual purpose: firstly, to promptly share noteworthy scientific advances and foster discussions among scientists, and secondly, to ensure the swift dissemination of scientific results globally, emphasizing their significance for knowledge, culture, and daily life.

Epithelial cell membrane perforation induces allergic airway inflammation

Published: 30 July 2025 DOI: 10.1038/s41586-025-09331-1
Kejian Shi, Yao Lv, Chunqiu Zhao, Huan Zeng, Yeqiong Wang, Yuxuan Liu, Lin Li, She Chen, Pu Gao, Feng Shao, Mo Xu

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III

Published: 11 June 2025 DOI: 10.1038/s41586-025-09090-z
Conor James McClune, Jack Chun-Ting Liu, Chloe Wick, Ricardo De La Peña, Bernd Markus Lange, Polly M. Fordyce, Elizabeth S. Sattely

Fetal hepatocytes protect the HSPC genome via fetuin-A

Published: 4 December 2024 DOI: 10.1038/s41586-024-08307-x
Xiao-Lin Guo, Yi-Ding Wang, Yan-Jun Liu, Lei Chu, Hua Zhu, Ye Hu, Ren-Yan Wu, Hong-Yu Xie, Juan Yu, Shui-Ping Li, Zhao-Yang Xiong, Ruo-Yan Li, Fang Ke, Lei Chen, Guo-Qiang Chen, Liang Chen, Fan Bai, Tariq Enver, Guo-Hong Li, Huai-Fang Li, Deng-Li Hong

In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution.

Published: 17 July 2024 DOI:
Peter F. Renz, Umesh Ghoshdastider, Simona Baghai Sain, Fabiola Valdivia-Francia, Ameya Khandekar, Mark Ormiston, Martino Bernasconi, Clara Duré, Jonas A. Kretz, Minkyoung Lee, Katie Hyams, Merima Forny, Marcel Pohly, Xenia Ficht, Stephanie J. Ellis, Andreas E. Moor, Ataman Sendoel

An atlas of epithelial cell states and plasticity in lung adenocarcinoma.

Published: 28 February 2024 DOI:
Guangchun Han, Ansam Sinjab, Zahraa Rahal, Anne M. Lynch, Warapen Treekitkarnmongkol, Yuejiang Liu, Alejandra G. Serrano, Jiping Feng, Ke Liang, Khaja Khan, Wei Lu, Sharia D. Hernandez, Yunhe Liu, Xuanye Cao, Enyu Dai, Guangsheng Pei, Jian Hu, Camille Abaya, Lorena I. Gomez-Bolanos, Fuduan Peng, Minyue Chen, Edwin R. Parra, Tina Cascone, Boris Sepesi, Seyed Javad Moghaddam, Paul Scheet, Marcelo V. Negrao, John V. Heymach, Mingyao Li, Steven M. Dubinett, Christopher S. Stevenson, Avrum E. Spira, Junya Fujimoto, Luisa M. Solis, Ignacio I. Wistuba, Jichao Chen, Linghua Wang, Humam Kadara

Multisensory gamma stimulation promotes glymphatic clearance of amyloid.

Published: 28 February 2024 DOI:
Mitchell H. Murdock, Cheng-Yi Yang, Na Sun, Ping-Chieh Pao, Cristina Blanco-Duque, Martin C. Kahn, TaeHyun Kim, Nicolas S. Lavoie, Matheus B. Victor, Md Rezaul Islam, Fabiola Galiana, Noelle Leary, Sidney Wang, Adele Bubnys, Emily Ma, Leyla A. Akay, Madison Sneve, Yong Qian, Cuixin Lai, Michelle M. McCarthy, Nancy Kopell, Manolis Kellis, Kiryl D. Piatkevich, Edward S. Boyden, Li-Huei Tsai

A novel antidiuretic hormone governs tumour-induced renal dysfunction.

Published: 6 December 2023 DOI: 10.1038/s41586-023-06833-8
Wenhao Xu, Gerui Li, Yuan Chen, Xujun Ye, Wei Song

Ligand recognition and G-protein coupling of trace amine receptor TAAR1

Published: 7 November 2023 DOI: 10.1038/s41586-023-06804-z
Zheng Xu, Lulu Guo, Jingjing Yu, Siyuan Shen, Chao Wu, Weifeng Zhang, Chang Zhao, Yue Deng, Xiaowen Tian, Yuying Feng, Hanlin Hou, Lantian Su, Hongshuang Wang, Shuo Guo, Heli Wang, Kexin Wang, Peipei Chen, Jie Zhao, Xiaoyu Zhang, Xihao Yong, Lin Cheng, Lunxu Liu, Shengyong Yang, Fan Yang, Xiaohui Wang, Xiao Yu, Yunfei Xu, Jin-Peng Sun, Wei Yan, Zhenhua Shao

Recognition of methamphetamine and other amines by trace amine receptor TAAR1

Published: 7 November 2023 DOI: 10.1038/s41586-023-06775-1
Heng Liu, You Zheng, Yue Wang, Yumeng Wang, Xinheng He, Peiyu Xu, Sijie Huang, Qingning Yuan, Xinyue Zhang, Ling Wang, Kexin Jiang, Hong Chen, Zhen Li, Wenbin Liu, Sheng Wang, H. Eric Xu, Fei Xu

GPCR activation and GRK2 assembly by a biased intracellular agonist

Published: 2 August 2023 DOI: 10.1038/s41586-023-06395-9
Jia Duan, Heng Liu, Fenghui Zhao, Qingning Yuan, Yujie Ji, Xiaoqing Cai, Xinheng He, Xinzhu Li, Junrui Li, Kai Wu, Tianyu Gao, Shengnan Zhu, Shi Lin, Ming-Wei Wang, Xi Cheng, Wanchao Yin, Yi Jiang, Dehua Yang, H. Eric Xu

Structural basis for directional chitin biosynthesis

Published: 21 September 2022 DOI: 10.1038/s41586-022-05244-5
Wei Chen, Peng Cao, Yuansheng Liu, Ailing Yu, Dong Wang, Lei Chen, Rajamanikandan Sundarraj, Zhiguang Yuchi, Yong Gong, Hans Merzendorfer, Qing Yang

Hormone- and antibody-mediated activation of the thyrotropin receptor.

Published: 8 August 2022 DOI: 10.1038/s41586-022-05173-3
Jia Duan, Peiyu Xu, Xiaodong Luan, Yujie Ji, Xinheng He, Ning Song, Qingning Yuan, Ye Jin, Xi Cheng, Hualiang Jiang, Jie Zheng, Shuyang Zhang, Yi Jiang, H. Eric Xu

Reconstructed covalent organic frameworks

Published: 6 April 2022 DOI: 10.1038/s41586-022-04443-4
Weiwei Zhang, Linjiang Chen, Sheng Dai, Chengxi Zhao, Cheng Ma, Lei Wei, Minghui Zhu, Samantha Y. Chong, Haofan Yang, Lunjie Liu, Yang Bai, Miaojie Yu, Yongjie Xu, Xiao-Wei Zhu, Qiang Zhu, Shuhao An, Reiner Sebastian Sprick, Marc A. Little, Xiaofeng Wu, Shan Jiang, Yongzhen Wu, Yue-Biao Zhang, He Tian, Wei-Hong Zhu, Andrew I. Cooper

Structures of full-length glycoprotein hormone receptor signalling complexes

Published: 22 September 2021 DOI: 10.1038/s41586-021-03924-2
Jia Duan, Peiyu Xu, Xi Cheng, Chunyou Mao, Tristan Croll, Xinheng He, Jingjing Shi, Xiaodong Luan, Wanchao Yin, Erli You, Qiufeng Liu, Shuyang Zhang, Hualiang Jiang, Yan Zhang, Yi Jiang, H. Eric Xu

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.

Published: 11 November 2020 DOI: 10.1038/s41586-020-2928-y
Xiao-Yi Lu, Xiong-Jie Shi, Ao Hu, Ju-Qiong Wang, Yi Ding, Wei Jiang, Ming Sun, Xiaolu Zhao, Jie Luo, Wei Qi, Bao-Liang Song

Structure of M pro from SARS-CoV-2 and discovery of its inhibitors.

Published: 9 April 2020 DOI: 10.1038/s41586-020-2223-y
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng, Meiqin Liu, Yao Zhao, Bing Zhang, Xiaofeng Li, Leike Zhang, Chao Peng, Yinkai Duan, Jing Yu, Lin Wang, Kailin Yang, Fengjiang Liu, Rendi Jiang, Xinglou Yang, Tian You, Xiaoce Liu, Xiuna Yang, Fang Bai, Hong Liu, Xiang Liu, Luke W. Guddat, Wenqing Xu, Gengfu Xiao, Chengfeng Qin, Zhengli Shi, Hualiang Jiang, Zihe Rao, Haitao Yang