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Pharmaceuticals

IF:4.3 CiteScore:6.1 Articles:1332

Pharmaceuticals (ISSN 1424-8247) is an international scientific journal of medicinal chemistry and related drug sciences.

Screening of an FDA-Approved Drug Library: Menadione Induces Multiple Forms of Programmed Cell Death in Colorectal Cancer Cells via MAPK8 Cascades

Published: 31 July 2025 DOI: 10.3390/ph18081145
Liyuan Cao, Weiwei Song, Jinli Sun, Yang Ge, Wei Mu, Lei Li

Protective Effects of Pasireotide in LPS-Induced Acute Lung Injury

Published: 22 June 2025 DOI: 10.3390/ph18070942
Saikat Fakir, Md Matiur Rahman Sarker, Madan Sigdel, Nektarios Barabutis

Huanglian Jiedu Decoction Treats Ischemic Stroke by Regulating Pyroptosis: Insights from Multi-Omics and Drug–Target Relationship Analysis

Published: 23 May 2025 DOI: 10.3390/ph18060775
Yixiao Gu, Zijin Sun, Tao Li, Xia Ding

Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway

Published: 20 February 2025 DOI: 10.3390/ph18030287
Yi Liu, Ling Yao, Yuanyuan Liu, Yunheng Yang, Ailing Liang, Honglin He, Yao Lei, Wenfu Cao, Zhiwei Chen

Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites

Published: 3 January 2025 DOI: 10.3390/ph18010050
Alessandra Viperino, Michael Höpfner, Nicole Edel, Ibrahim S Al Nasr, Waleed S Koko, Tariq A Khan, Imen Ben Abdelmalek, Rainer Schobert, Bernhard Biersack, Bianca Nitzsche

Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Validation

Published: 25 December 2024 DOI: 10.3390/ph18010012
Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

Dehydroepiandrosterone and Its Metabolite 5-Androstenediol: New Therapeutic Targets and Possibilities for Clinical Application.

Published: 9 September 2024 DOI: 10.3390/ph17091186
Tatiana A Fedotcheva, Maria E Uspenskaya, Darya N Ulchenko, Nikolay L Shimanovsky

Sinomenium acutum Modulates Platelet Aggregation and Thrombus Formation by Regulating the Glycoprotein VI-Mediated Signalosome in Mice

Published: 20 December 2023 DOI: 10.3390/ph17010006
Yeon-Ji Kim, Tae In Kim, Ami Lee, Kyungho Kim, Youn-Hwan Hwang

Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)

Published: 3 November 2023 DOI: 10.3390/ph16111557
Agnieszka Pawlak, Bartosz Kaczmarek, Adam Wysokiński, Dominik Strzelecki

Identification of Potential RBPJ-Specific Inhibitors for Blocking Notch Signaling in Breast Cancer Using a Drug Repurposing Strategy

Published: 29 April 2022 DOI: 10.3390/ph15050556
Mengjie Rui, Min Cai, Yu Zhou, Wen Zhang, Liang Gao, K. Mi, Wei Ji, Dan Wang, Chunlai Feng

Carpaine Promotes Proliferation and Repair of H9c2 Cardiomyocytes after Oxidative Insults

Published: 1 February 2022 DOI: 10.3390/ph15020230
Suhaini Sudi, Yee-Zheng Chin, Nur Syafinaz Wasli, S. Fong, S. C. Shimmi, S. How, Caroline Sunggip