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Phytotherapy Research

IF:6.1 CiteScore:12.8 Articles:325

Phytotherapy Research is an internationally recognized pharmacological journal that serves as a trailblazing resource for biochemists, pharmacologists, and toxicologists. We strive to disseminate groundbreaking research on medicinal plants, pushing the boundaries of knowledge and understanding in this field. Our primary focus areas encompass pharmacology, toxicology, and the clinical applications of herbs and natural products in medicine. We actively encourage submissions on the effects of commonly consumed food ingredients and standardized plant extracts. We welcome a range of contributions including original research papers, review articles, and letters. By providing a platform for the latest developments and discoveries in phytotherapy, we aim to support the advancement of scientific knowledge and contribute to the improvement of modern medicine.

Non-Apoptotic Inhibition of Colorectal Cancer Proliferation by Sclareol via Ferroptosis Involving SLC7A11/GPX4 Modulation.

Published: 1 October 2025 DOI: 10.1002/ptr.70010
Yu-Xi Li, Yuan Wu, Qiong Li, Yu-Qing Huang, Ying-Ying Yuan, Yan-Ni Su, Chien-Shan Cheng, Lan Zheng

Scutebarbatine B Exerts Anti-Breast Cancer Activity by Inducing Cell Cycle Arrest and Apoptosis Through Multiple Pathways

Published: 1 August 2025 DOI: 10.1002/ptr.70007
Chong Niu, Ruo-Tong Li, Xiao-Shan Hao, Xiao Qi, Feng-Ze Wang, Hong-Rong Fei

Oxyimperatorin Suppresses the Pathologies of Rheumatoid Arthritis and the Growth of Synovial Organoids Through Targeting the PI3K/AKT Pathway

Published: 1 August 2025 DOI: 10.1002/ptr.70009
Xu Gao, Shuyan Lyu, Tengyu Lin, Juan He, Weiye Pan, Jiaxin He, Xiaocheng Wang, Xian Lin, Jian Chen, Qingwen Wang

Portulaca oleracea L. Extract and Its Alkaloid Oleracein E Alleviates Cardiac Remodeling and Heart Failure in Mice by Targeting STAT2 Through the MAPK Signaling Inflammatory Pathway

Published: 27 April 2025 DOI: 10.1002/ptr.8501
Risheng Zhao, Min Zhang, Gege Yang, Wei Liu, Hui Yu, Shuang Yan, Ting Ren, Linxin Zhang, Mengyang Wang, Haiming Sun

Artemether Ameliorates Non‐Alcoholic Steatohepatitis by Restraining Cross‐Talk Between Lipotoxicity‐Induced Hepatic Hepatocytes and Macrophages

Published: 28 November 2024 DOI: 10.1002/ptr.8393
Jia Xu, Xiaoyan Cheng, Qi Wang, Feng Zhang, Xinxin Ren, Kunlun Huang, Yanzhou Hu, Ruxin Gao, Kun Yang, Jingya Yin, Bingqing Yang, Xiaoyun He, Yue Li

Harmine promotes megakaryocyte differentiation and thrombopoiesis by activating the Rac1/Cdc42/JNK pathway through a potential target of 5-HTR2A

Published: 1 November 2024 DOI: 10.1002/ptr.8317
Xiaoxi Liu, Jia Lai, Xiaoqin Zhang, Anguo Wu, Ling Zhou, Yueyue Li, Qianqian Huang, Xinwu Huang, Hua Li, Cai Lan, Jian Liu, Feihong Huang, Jianming Wu

Calycosin inhibits the proliferation and metastasis of renal cell carcinoma through the MAZ/HAS2 signaling pathway

Published: 1 September 2024 DOI: 10.1002/ptr.8295
Zi-Hao Zhang, Cheng-Yue Yuan, Meng Xu, Meng-Fei Wang, Tao Feng, Yue Wang, Sheng-Feng Zheng, Hai-Liang Zhang, Guo-Hai Shi, Da-Long Cao, Zi-Liang Wang, Ding-Wei Ye

Phillygenin prevents osteoclast differentiation and bone loss by targeting RhoA

Published: 1 April 2024 DOI: 10.1002/ptr.8074
Jiahui Zhang, Tao Jiang, Yuxin Zhang, Kai Yang, Yichen Zhao, Qi Zhou, Zhuo Yang, Renhao Yang, Ruonan Ning, Tao Liu, Lianfu Deng, Xiaobing Xi, Xing Xu, Min Jiang

A new look at angiogenesis inhibition of geniposide in experimental arthritis by blocking angiopoietin-2 exocytosis

Published: 1 March 2024 DOI: 10.1002/ptr.8094
Peirong Gan, Hong Wu, Yulong Zhu, Yin Shu, Yi Wei

Taxifolin-mediated Nrf2 activation ameliorates oxidative stress and apoptosis for the treatment of glucocorticoid-induced osteonecrosis of the femoral head

Published: 1 January 2024 DOI: 10.1002/ptr.8031
Hongyi Jiang, Chihao Lin, Tingwen Cai, Liting Jiang, Chao Lou, Shida Lin, Weidan Wang, Zijian Yan, Xiaoyun Pan, Xinghe Xue

Lutein inhibits tumor progression through the ATR/Chk1/p53 signaling pathway in non-small cell lung cancer.

Published: 1 April 2023 DOI: 10.1002/ptr.7682
Si-Yu Zhang, You-Yi Lu, Xin-Liang He, Yuan Su, Fen Hu, Xiao-Shan Wei, Min-Jie Pan, Qiong Zhou, Wei-Bing Yang

Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches.

Published: 1 January 2022 DOI: 10.1002/ptr.7324
Bin Zeng, Ailing Wei, Qiang Zhou, Minghao Yuan, Kelu Lei, Yushi Liu, Jiawen Song, Li Guo, Qiang Ye

Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans.

Published: 1 March 2010 DOI: 10.1002/ptr.3074
Karin Woelkart, Elisabeth Feizlmayr, Peter Dittrich, Eckhard Beubler, Fritz Pinl, Andy Suter, Rudolf Bauer