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PLoS Pathogens

PLoS Pathogens

IF:4.9 CiteScore:11.4 Articles:598
Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function.

Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection

Published: 1 April 2023 DOI: 10.1371/journal.ppat.1011317
Mason R Firpo, Natalie J LoMascolo, Marine J Petit, Priya S Shah, Bryan C Mounce

The type three secretion system effector protein IpgB1 promotes Shigella flexneri cell-to-cell spread through double-membrane vacuole escape

Published: 24 February 2022 DOI: 10.1371/journal.ppat.1010380
Erin A Weddle, Volkan K Köseoğlu, Brittany A DeVasure, Hervé F Agaisse

Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung

Published: 17 February 2022 DOI: 10.1371/journal.ppat.1010343
Xinxin Wang, Jie Luo, Zhiyuan Wen, Lei Shuai, Chong Wang, Gongxun Zhong, Xijun He, Huizhen Cao, Renqiang Liu, Jinying Ge, Ronghong Hua, Ziruo Sun, Xijun Wang, Jinliang Wang, Zhigao Bu

The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host

Published: 8 September 2021 DOI: 10.1371/journal.ppat.1009917
Zhaojiang Guo, Shi Kang, Qingjun Wu, Shaoli Wang, Neil Crickmore, Xuguo Zhou, Alejandra Bravo, Mario Soberón, Youjun Zhang

A novel cell culture system modeling the SARS-CoV-2 life cycle

Published: 12 March 2021 DOI: 10.1371/journal.ppat.1009439
Xiaohui Ju, Yunkai Zhu, Yuyan Wang, Jingrui Li, Jiaxing Zhang, Mingli Gong, Wenlin Ren, Sai Li, Jin Zhong, Linqi Zhang, Qiangfeng Cliff Zhang, Rong Zhang, Qiang Ding

Scavenger receptor-C acts as a receptor for Bacillus thuringiensis vegetative insecticidal protein Vip3Aa and mediates the internalization of Vip3Aa via endocytosis

Published: 4 October 2018 DOI: 10.1371/journal.ppat.1007347
Kun Jiang, Xiao-Yue Hou, Tong-Tong Tan, Zhang-Lei Cao, Si-Qi Mei, Bing Yan, Jin Chang, Lu Han, Dan Zhao, Jun Cai