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PLoS Pathogens

IF:5.5 Articles:598

Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function.

Newcastle disease virus promotes spreading infection through vimentin-dependent tight junction injury mediated by MLC/p-MLC activation

Published: 29 August 2025 DOI: 10.1371/journal.ppat.1013458
Xiaolong Lu, Qiwen Zhou, Mingzhu Wang, Meiqi Li, Wenhao Yang, Kaituo Liu, Ruyi Gao, Tianxing Liao, Yu Chen, Jiao Hu, Min Gu, Shunlin Hu, Xinan Jiao, Xiaoquan Wang, Xiufan Liu, Chan Ding, Xiaowen Liu

The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor

Published: 16 July 2025 DOI: 10.1371/journal.ppat.1013319
Haojie Ren, Yanjin Wang, Lian-Feng Li, Lan-Fang Shi, Yu-He Ma, Jun-Hao Fan, Xiao-Ya Pan, Han-Cheng Shao, Yuhang Zhang, Shichong Han, Bo Wan, Hua-Ji Qiu, Gai-Ping Zhang, Su Li, Wen-Rui He

Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein

Published: 30 January 2025 DOI: 10.1371/journal.ppat.1012897
Qian Qiu, Zihan He, Jing Liu, Huijun Xu, Jinyu Wang, Nannan Liu, Ning Kang, Shaokun Pan, Weien Yu, Zixiang Gao, Shimei Zhang, Yang Yang, Qiang Deng, Youhua Xie, Jiming Zhang, Zhongliang Shen

KSHV hijacks the antiviral kinase IKKε to initiate lytic replication

Published: 17 January 2025 DOI: 10.1371/journal.ppat.1012856
Xiaoqian Wang, Zhenshan Liu, Xue Xu, Xin Wang, Zizhen Ming, Chengrong Liu, Hang Gao, Tingting Li, Qiming Liang

Skin as outermost immune organ of vertebrates that elicits robust early immune responses after immunization with glycoprotein of spring viraemia of carp virus

Published: 9 December 2024 DOI: 10.1371/journal.ppat.1012744
Zhao Zhao, Liang Zhao, Xue-Feng Wei, Yi-Jun Jia, Bin Zhu

Newcastle disease virus infection induces parthanatos in tumor cells via calcium waves.

Published: 2 December 2024 DOI: 10.1371/journal.ppat.1012737
Yang Qu, Siyuan Wang, Hui Jiang, Ying Liao, Xusheng Qiu, Lei Tan, Cuiping Song, Venugopal Nair, Zengqi Yang, Yingjie Sun, Chan Ding