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Stem Cell Research & Therapy

IF:7.1 CiteScore:13.2 Articles:525

Stem Cell Research & Therapy serves as a leading platform for translational research in stem cell therapies. This international, peer-reviewed journal publishes high-quality open-access research articles, with a focus on basic, translational, and clinical research in stem cell therapeutics and regenerative therapies. Coverage includes animal models and clinical trials. Additionally, the journal offers reviews, viewpoints, commentaries, and reports.

Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease

Published: 21 October 2025 DOI: 10.1186/s13287-025-04737-0
Mark-Christian Klassen, Anita Balázs, Janina Zöllner, Nicole Cleve, Laurien Czichon, Laura von Schledorn, Jan Hegermann, Janna C Nawroth, Doris Roth, Mia Mielenz, Silke Hedtfeld, Frauke Stanke, Tihomir Rubil, Fabio Ius, Danny Jonigk, John W Hanrahan, Arjang Ruhparwar, Ruth Olmer, Marcus A Mall, Sylvia Merkert, Ulrich Martin

PRMT1 inhibition enhances the cardioprotective effect of adipose-derived mesenchymal stem cells against myocardial infarction through RUNX1

Published: 3 June 2025 DOI: 10.1186/s13287-025-04409-z
Dongdong Du, Ting Wang, Yaodong Sun, Yi Zhang, Bufan Zhang, Jingrong Shao, Mengxue Yang, Chuan Huang, Shengkai Zuo, Naishi Wu

CX43-mediated mitochondrial transfer maintains stemness of KG-1a leukemia stem cells through metabolic remodeling

Published: 2 December 2024 DOI: 10.1186/s13287-024-04079-3
Huihui Fu, Xiaoqing Xie, Liuyue Zhai, Yi Liu, Yifeng Tang, Sanxiu He, Jun Li, Qing Xiao, Guofa Xu, Zailin Yang, Xiaomei Zhang, Yao Liu

Secretome from iPSC-derived MSCs exerts proangiogenic and immunosuppressive effects to alleviate radiation-induced vascular endothelial cell damage.

Published: 29 July 2024 DOI: 10.1186/s13287-024-03847-5
Kshama Gupta, Ralph B Perkerson, Tammee M Parsons, Ramacharan Angom, Danilyn Amerna, Jeremy D Burgess, Yingxue Ren, Pamela J McLean, Debabrata Mukhopadhyay, Prasanna Vibhute, Zbigniew K Wszolek, Abba C Zubair, Alfredo Quiñones-Hinojosa, Takahisa Kanekiyo

Co-culture pellet of human Wharton’s jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study

Published: 30 July 2022 DOI: 10.1186/s13287-022-03094-6
Kaiwen Zheng, Yiyang Ma, Cheng Chiu, Yidan Pang, Junjie Gao, Changqing Zhang, Dajiang Du

BMSC-derived extracellular vesicles intervened the pathogenic changes of scleroderma in mice through miRNAs

Published: 5 June 2021 DOI: 10.1186/s13287-021-02400-y
Jiahui Jin, Qingjian Ou, Zhe Wang, Haibin Tian, Jing-Ying Xu, Furong Gao, Shuqin Hu, Jie Chen, Juan Wang, Jieping Zhang, Lixia Lu, Caixia Jin, Guo-Tong Xu, Jingjun Zhao

Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells

Published: 27 July 2018 DOI: 10.1186/s13287-018-0934-x
Fuyu Duan, Rujin Huang, Fengzhi Zhang, Yonglin Zhu, Lin Wang, Xia Chen, Lufeng Bai, Wei Guo, Sophia Chia-Ning Chang, Xiaoyu Hu, Jie Na