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Theranostics

IF:13.3 CiteScore:25.4 Articles:433

Theranostics serves as a pivotal platform for the exchange of clinical and scientific insights within the diagnostic and therapeutic molecular and nanomedicine community, along with allied professions engaged in integrating molecular imaging and therapy. As a multidisciplinary journal, Theranostics showcases innovative research articles spanning fields such as in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensor technology, nanobiosensors, bioelectronics, system biology, translational medicine, point-of-care applications, and personalized medicine. Encouraging a broad spectrum of biomedical research with potential theranostic applications, the journal rigorously peer-reviews primary research, alongside publishing reviews, news, and commentary that aim to bridge the gap between the laboratory, clinic, and biotechnology industries.

BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner

Published: 13 April 2025 DOI: 10.7150/thno.110122
Xianyang Liu, Shuhao Zeng, Jiayu Meng, Qian Zhou, Fan Cao, Baorui Chu, Chao Wu, Yakun Wang, Hui Feng, Xiaorui Bi, Xinyuan Chen, Wenxian Yang, Meng Tian, Hui Yang, Ke Hu, Shengping Hou

ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation

Published: 22 July 2024 DOI: 10.7150/thno.95796
Na Cui, Chengyu Liu, Xiang Tang, Liangliang Song, Zixuan Xiao, Chen Wang, Yancai Wu, Yihao Zhou, Chentai Peng, Yuxia Liu, Ling Zheng, Xinran Liu, Kun Huang, Hong Chen

The CEBPB + glioblastoma subcluster specifically drives the formation of M2 tumor-associated macrophages to promote malignancy growth.

Published: 2 July 2024 DOI: 10.7150/thno.93473
Yongchang Yang, Xingyu Jin, Yang Xie, Chunlan Ning, Yiding Ai, Haotian Wei, Xing Xu, Xianglian Ge, Tailong Yi, Qiang Huang, Xuejun Yang, Tao Jiang, Xiaoguang Wang, Yingzhe Piao, Xun Jin

Caspase-mediated AURKA cleavage at Asp132 is essential for paclitaxel to elicit cell apoptosis

Published: 17 June 2024 DOI: 10.7150/thno.97842
Xiaoting Chen, Shujuan Du, Yulin Zhang, Ke Peng, Lina Liu, Ting Wang, Hao Zhang, Shen Cai, Caixia Zhu, Youhai Li, Wen Tuo, Yuyan Wang, Fang Wei, Qiliang Cai

LINC00982-encoded protein PRDM16-DT regulates CHEK2 splicing to suppress colorectal cancer metastasis and chemoresistance

Published: 27 May 2024 DOI: 10.7150/thno.95485
Hui-Fang Hu, Lei Han, Jia-Ying Fu, Xuan He, Ji-Feng Tan, Qing-Ping Chen, Jing-Ru Han, Qing-Yu He

Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice

Published: 28 April 2024 DOI: 10.7150/thno.94482
Yaling Chen, Tong Wang, Fuxiang Liang, Jia Han, Zhiling Lou, Yifan Yu, Jinsheng Li, Tianwei Zhan, Yuqing Gu, Lingjun Dong, Bo Jiang, Weiping Zhang, Ming Wu, Yunbi Lu

Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury

Published: 1 January 2024 DOI: 10.7150/thno.88061
Shanshan Liu, Xinyu Xiao, La Zhang, Jianwei Wang, Wei Zhao, Haichuan Liu, Rui Liao, Zhi Li, Mengxia Xu, Jiao Guo, Baoyong Zhou, Chengyou Du, Qiling Peng, Ning Jiang

Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice

Published: 4 September 2023 DOI: 10.7150/thno.87968
Peng Xiang, Qingqiu Chen, Le Chen, Jin Lei, Zhiyi Yuan, Hui Hu, Yining Lu, Xianmin Wang, Tingting Wang, Ruihong Yu, Wanping Zhang, Jun Zhang, Chao Yu, Limei Ma

Tubular Elabela-APJ axis attenuates ischemia-reperfusion induced acute kidney injury and the following AKI-CKD transition by protecting renal microcirculation

Published: 4 June 2023 DOI: 10.7150/thno.84308
Mingrui Xiong, Hong Chen, Yu Fan, Muchuan Jin, Dong Yang, Yuchen Chen, Yu Zhang, Robert B Petersen, Hua Su, Anlin Peng, Congyi Wang, Ling Zheng, Kun Huang

pH-responsive hybrid platelet membrane-coated nanobomb with deep tumor penetration ability and enhanced cancer thermal/chemodynamic therapy

Published: 16 May 2022 DOI: 10.7150/thno.68996
Huang Yang, Yuang Ding, Zongrui Tong, Xiaohui Qian, Hao Xu, Feng-Wei Lin, Guoping Sheng, Liangjie Hong, Weilin Wang, Z. Mao

Fibroblast activation protein α activatable theranostic pro-photosensitizer for accurate tumor imaging and highly-specific photodynamic therapy

Published: 1 May 2022 DOI: 10.7150/thno.70308
Yong Luo, Zishan Zeng, Ting Shan, Xiaoyu Xu, Jie Chen, Yuanfeng He, Tao Zhang, Zeqian Huang, Guihong Chai, Yanjuan Huang, Yanfang Zhao, Chunshun Zhao

Ferroptotic stress promotes macrophages against intracellular bacteria

Published: 21 February 2022 DOI: 10.7150/thno.66663
Ruonan Ma, Ling Fang, Lei Chen, Xiaonan Wang, Jing Jiang, Lizeng Gao

Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2

Published: 1 January 2022 DOI: 10.7150/thno.76232
Dapeng Li, Anjiang Sun, Liang Zhang, Zhao Ding, Fangzheng Yi, Xue Yang, Zixi Wang, Xu Chen, Weiwei Liu, Shixian Liu, Hailong Shen, Manli Miao, Ling Zhang, Ping Liu, Yuchen Liu, Shihong Su, Hailiang Huang, Can Huang, Zhongdong Hu, Hongbing Zhang, Xiaojun Zha, Yehai Liu

CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders

Published: 17 October 2021 DOI: 10.7150/thno.66378
Hanju Yoo, Ha-Ri Lee, Ki-Hyun Kim, Min-Ah Kim, Seunghyun Bang, Young-Ho Kang, Woo-Hyung Kim, Youngsup Song, Sung Eun Chang

Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors

Published: 25 February 2021 DOI: 10.7150/thno.52077
Yiqun Xia, Jundixia Chen, Yun Yu, Fengjiao Wu, Xin Shen, Chenyu Qiu, Tingting Zhang, Lin Hong, Peisen Zheng, Rongrong Shao, Chenxin Xu, Fang Wu, Wei Chen, Congying Xie, Ri Cui, Peng Zou

Autophagy-lysosome inhibitor chloroquine prevents CTLA-4 degradation of T cells and attenuates acute rejection in murine skin and heart transplantation

Published: 1 July 2020 DOI: 10.7150/thno.43507
Jikai Cui, Jizhang Yu, Heng Xu, Yanqiang Zou, Hao Zhang, Shanshan Chen, Sheng Le, Jing Zhao, Lang Jiang, Jiahong Xia, Jie Wu

Therapeutic potential of targeting MKK3-p38 axis with Capsaicin for Nasopharyngeal Carcinoma

Published: 24 June 2020 DOI: 10.7150/thno.45191
Chengyao Chiang, Min Zhang, Dian Wang, Tian Xiao, Lizhi Zhu, Kai Chen, Junrong Huang, Jingying Huang, Jiang Zhu, Li Li, Cheng Chen, Yangchao Chen, Hongyi Hu, Wenqi Jiang, Yongdong Zou, Ting Wang, Duo Zheng

JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression

Published: 4 March 2020 DOI: 10.7150/thno.41502
Ji-Hye Kim, A-Reum Hong, Yo-Han Kim, Hanju Yoo, Sang-Wook Kang, Sung Eun Chang, Youngsup Song

Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening

Published: 18 September 2019 DOI: 10.7150/thno.34520
Zhen-yu Wang, Wei-Jian Li, Hong-Shu Jing, M. Ding, Gongbo Fu, Tianjie Yuan, Weijian Huang, Mengjun Dai, Dan Tang, Min Zeng, Yi Chen, Hongdan Zhang, Xuejing Zhu, Yuan-yuan Peng, Qigen Li, Wei-Feng Yu, Hexin Yan, B. Zhai

LncRNA AY promotes hepatocellular carcinoma metastasis by stimulating ITGAV transcription

Published: 9 June 2019 DOI: 10.7150/thno.32854
Chun Lan Kang, Bing Qi, Qian Qian Cai, Li Sheng Fu, Ying Yang, Chang Tang, Ping Zhu, Qi Wen Chen, Jing Pan, Mei Hua Chen, Xing Zhong Wu

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