The difference between natural luteolin and semi-synthetic luteolin

The difference between natural luteolin and semi-synthetic luteolin lies primarily in their sources and production methods:

1. Natural Luteolin:

   • Source: Natural luteolin is extracted directly from plants, such as celery, green peppers, and chamomile.

   • Extraction Process: It is obtained through methods like solvent extraction, column chromatography, or other purification techniques.

   • Purity and Composition: It may contain trace amounts of other flavonoids or plant compounds, depending on the extraction process.

2. Semi-Synthetic Luteolin:

   • Source: Semi-synthetic luteolin is typically derived from chemical synthesis or modification of natural precursors.

   • Production Process: It involves chemical reactions to convert related compounds (e.g., other flavonoids or intermediates) into luteolin.

   • Purity and Composition: It is often more standardized and pure, as the synthesis process can be tightly controlled.

In summary, natural luteolin is directly sourced from plants, while semi-synthetic luteolin is produced through chemical processes, often resulting in higher purity and consistency.