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What are the differences in the effectiveness of using blood anticoagulants heparin sodium and heparin lithium?

Release time: 2023-10-12

 
Everyone knows that heparin lithium and heparin sodium are both made from heparin extracts and used as anticoagulants in blood collection. From the principle of application, both heparin sodium and heparin lithium can inhibit the activity of thrombin, thereby preventing blood clotting. But from the perspective of detection, the usage effects of the two are different. Let's take a look together!
 
The difference between heparin sodium and heparin lithium:
1. The ions combined are different: although the anticoagulation principles of the two substances are similar, the ion size and radius of the two substances are different, which affects their chemical reactivity.
 
2. The results of white blood cell counting are different: the changes in white blood cells detected by heparin sodium are more regular and the results are more accurate. The range of changes in the detection value of heparin lithium is not significant, and the white blood cell count is slow and stable, so the results obtained also have differences.
 
3. Different application ranges: Heparin lithium is often used in whole blood testing and analysis because it can complete analysis and testing in a short period of time. Heparin sodium is commonly used for whole kidney function testing, whole liver function testing, etc.
 
4. Different dosages used: According to industry standards, the dosage range for adding heparin lithium per milliliter of blood is 9.4IU-28IU, and the dosage range for adding heparin sodium is 12IU-30IU.
 
Although both heparin lithium and heparin sodium are heparin extracts, there are differences in both dosage and efficacy. Although both are blood anticoagulants, in practical applications, appropriate reagents should be selected based on one's own experimental needs for use.
 
Xindesheng is a professional manufacturer of heparin lithium and heparin sodium. Currently, the purity of heparin lithium/sodium produced can reach over 99%, and it has an independent research and development team. The product quality is reliable and the effect is stable. And through the ISO9001 quality control system, the quality is strictly controlled by professional personnel. If you need to make a purchase, please feel free to call us for consultation and ordering at any time!