Ibuprofen
Ibuprofen
- CAS:
- 15687-27-1
- MF:
- C13H18O2
- MW:
- 206.28
Suppliers by country/region
- India(147)
- CHINA(343)
- United States(82)
- Germany(23)
- Russia(1)
- Canada(9)
- United Kingdom(23)
- France(7)
- Europe(3)
- Japan(6)
- Switzerland(8)
- South Korea(3)
- Belgium(3)
- Ukraine(2)
- Norway(1)
- Philippines(1)
- Slovenia(1)
- Brazil(5)
- Egypt(2)
- Poland(3)
- The Netherlands(5)
- Italy(1)
- Argentina(2)
- Spain(3)
- Venezuela(1)
- Mexico(3)
- United Arab Emirates(1)
- Austria(1)
- Bangladesh(1)
- Greece(1)
- Nepal(1)
- Malaysia(1)
- Indonesia(1)
Company Type
Properties
- Melting point:
- 77-78 °C
- alpha
- [α]D20 -1～+1°(c=1,C2H5OH)
- Boiling point:
- 157 °C (4 mmHg)
- Density
- 1.0364 (rough estimate)
- refractive index
- 1.5500 (estimate)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.
- pka
- pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)
- form
- Crystalline Powder
- color
- white to off-white
- biological source
- synthetic (organic)
- Water Solubility
- insoluble
- Merck
- 14,4881
- BCS Class
- 2
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- HEFNNWSXXWATRW-UHFFFAOYSA-N
- LogP
- 3.970
- CAS DataBase Reference
- 15687-27-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Ibuprofen(15687-27-1)
- EPA Substance Registry System
- Benzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)- (15687-27-1)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H319-H335
- Precautionary statements
- P261-P264-P270-P271-P301+P312-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-63-51/53-39/23/24/25-23/24/25-11
- Safety Statements
- 36-61-36/37-45-16-7
- HS Code
- 29163920
- Hazardous Substances Data
- 15687-27-1(Hazardous Substances Data)
- Toxicity
- LD50 in male mice, rats (mg/kg): 495, 626 i.p.; 1255, 1050 orally (Orzalesi)
Use
Ibuprofen (Advil, Motrin) is used as an analgesic and antipyretic as well as a treatment for rheumatoid arthritis and degenerative joint disease. The most frequently observed side effects are nausea, heartburn, epigastric pain, rash, and dizziness. Incidence of GI side effects is lower than with indomethacin.Visual changes and cross-sensitivity to aspirin have been reported. Ibuprofen inhibits COX-1 and COX-2 about equally. It decreases platelet aggregation, but the duration is shorter and the effect quantitatively lower than with aspirin. Ibuprofen prolongs bleeding times toward high normal value and should be used with caution in patients who have coagulation deficits or are receiving anticoagulant therapy.
147 India supplier list of "Ibuprofen"
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Ahmedabad,INDIA
- Product Name:Ibuprofen
- Products Intro:Brand:trivenichemical | Product Number:816637510
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:2-[4-(2-methylpropyl)phenyl]propanoicacid
- Products Intro:Brand:thermofisher.in | Product Number:258610100 | Purity:99%
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Ibuprofen
- Products Intro:Brand:clearsynth | Product Number:CS-O-01647
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Ibuprofen
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA