Chemical Safety Data Sheet MSDS / SDS
1,2-EPOXYBUTANE
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: 1,2-EPOXYBUTANE
- CBnumber: CB5263486
- CAS: 106-88-7
- EINECS Number: 203-438-2
- Synonyms: Oxirane,ethyl- ;2-Ethyloxirane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
Hazard statements
H225 Highly Flammable liquid and vapour
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H351 Suspected of causing cancer
Substance
- Product name: 1,2-EPOXYBUTANE
- Synonyms: Oxirane,ethyl- ;2-Ethyloxirane
- CAS: 106-88-7
- EC number: 203-438-2
- MF: C4H8O
- MW: 72.11
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
3
2
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage class
Storage class (TRGS 510): 3: Flammable liquids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
8.1 Control parameters
Ingredients with workplace control parameters8.2 Exposure controls
Personal protective equipmentEye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact
Material: Fluorinated rubber
Minimum layer thickness: 0,7 mm
Break through time: 37 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact
Material: Fluorinated rubber
Minimum layer thickness: 0,7 mm
Break through time: 37 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) AppearanceForm: liquid
Color: colorless - b) Odorunpleasant
- c) Odor ThresholdNo data available
- d) pH7 at 50 g/l at 20 °C
- e) Melting point/freezing pointMelting point: -129,5 °C - (ECHA)
- f) Initial boiling point and boiling range63 °C - lit.
- g) Flash point-15 °C - closed cup
- h) Evaporation rateNo data available
- i) Flammability (solid, gas)No data available
- j) Upper/lower flammability or explosive limitsUpper explosion limit: 19 %(V)
Lower explosion limit: 1,7 %(V) - k) Vapor pressure187 hPa at 20 °C
- l) Vapor density2,49 - (Air = 1.0)
- m) Density0,829 g/cm3 at 25 °C - lit.
- Relative density0.829 g/mL at 20 °C(lit.)
- n) Water solubility86,8 g/l at 25 °C
- o) Partition coefficient: n-octanol/waterlog Pow: 0,68 at 25 °C - Bioaccumulation is not expected., (ECHA)
- p) Autoignition temperature370 °C at 1.013,25 hPa - DIN 51794
- q) Decomposition temperatureDistillable in an undecomposed state at normal pressure.
- r) ViscosityViscosity, kinematic: 0,51 mm2/s at 20 °C 0,42 mm2/s at 40 °C
Viscosity, dynamic: 0,421 mPa.s at 20 °C 0,34 mPa.s at 40 °C - s) Explosive propertiesNo data available
- t) Oxidizing propertiesNo data available
- Solubility86.8g/l
- Physical stateColorless liquid with pungent odor
- ColourColorless to Almost colorless
9.2 Other safety information
Relative vapor density2,49 - (Air = 1.0)
10.1 Reactivity
Vapors may form explosive mixture with air.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Risk of ignition or formation of inflammable gases or vapours with:
Strong oxidizing agents
Violent reactions possible with: alkali hydroxides
Ammonia
Chlorine
Acids
Bases
Alcohols metallic salts
Violent polymerization may be caused by:
Acids alkali hydroxides metallic chlorides aluminium chloride
Strong oxidizing agents
Violent reactions possible with: alkali hydroxides
Ammonia
Chlorine
Acids
Bases
Alcohols metallic salts
Violent polymerization may be caused by:
Acids alkali hydroxides metallic chlorides aluminium chloride
10.4 Conditions to avoid
Warming.
10.5 Incompatible materials
Copper, Copper alloys
10.6 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - 900 mg/kg
Remarks: (ECHA)
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute toxicity estimate Inhalation - 4 h - 11,1 mg/l (Expert judgment)
Acute toxicity estimate Inhalation - 4 h - 11,1 mg/l (Expert judgment)
Inhalation: Irritating to respiratory system.
LD50 Dermal - Rabbit - 1.743 mg/kg
Remarks: (RTECS)
Skin corrosion/irritation
Remarks: (ECHA)
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute toxicity estimate Inhalation - 4 h - 11,1 mg/l (Expert judgment)
Acute toxicity estimate Inhalation - 4 h - 11,1 mg/l (Expert judgment)
Inhalation: Irritating to respiratory system.
LD50 Dermal - Rabbit - 1.743 mg/kg
Remarks: (RTECS)
Causes skin irritation. Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation. - 20 h
Remarks: (ECHA)
Respiratory or skin sensitization
Result: Causes serious eye irritation. - 20 h
Remarks: (ECHA)
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Laboratory experiments have shown mutagenic effects.
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: positive
Carcinogenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: positive
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Respiratory system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: EK3675000
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - > 100 mg/l - 96 h (DIN 38412 part 15)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 70 mg/l - 48 h and other aquatic (Regulation (EC) No. 440/2008, Annex, C.2) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - > 500 mg/l - 72 h (DIN 38412)
Toxicity to bacteria static test EC50 - activated sludge - ca. 900 mg/l - 30 min (OECD Test Guideline 209)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 70 mg/l - 48 h and other aquatic (Regulation (EC) No. 440/2008, Annex, C.2) invertebrates
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - > 500 mg/l - 72 h (DIN 38412)
Toxicity to bacteria static test EC50 - activated sludge - ca. 900 mg/l - 30 min (OECD Test Guideline 209)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 80 - 90 % - Readily biodegradable.
(ISO 14593)
Result: 80 - 90 % - Readily biodegradable.
(ISO 14593)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
No data available
13.1 Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
14.1 UN number
ADR/RID: 3022
IMDG: 3022
IATA: 3022
IMDG: 3022
IATA: 3022
14.2 UN proper shipping name
ADR/RID: 1,2-BUTYLENE OXIDE, STABILIZED
IMDG: 1,2-BUTYLENE OXIDE, STABILIZED
IATA: 1,2-Butylene oxide, stabilized
IMDG: 1,2-BUTYLENE OXIDE, STABILIZED
IATA: 1,2-Butylene oxide, stabilized
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA: 3
IMDG: 3
IATA: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA: II
IMDG: II
IATA: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA: no
IMDG Marine pollutant: no
IATA: no
14.6 Special precautions for user
No data available
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the European : FLAMMABLE LIQUIDS
Parliament and of the Council on the control of major-accident hazards involving dangerous substances.
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the European : FLAMMABLE LIQUIDS
Parliament and of the Council on the control of major-accident hazards involving dangerous substances.
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.