Chemical Safety Data Sheet MSDS / SDS


Revision Date:2023-05-06Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 2,4-Dinitrophenol
  • CBnumber: CB6358550
  • CAS: 51-28-5
  • EINECS Number: 200-087-7
  • Synonyms: 2,4-dinitrophenol,2,4-DNP

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311 Call a POISON CENTER or doctor/physician.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Hazard statements
H225 Highly Flammable liquid and vapour
H228 Flammable solid
H300 Fatal if swallowed
H310 Fatal in contact with skin
H330 Fatal if inhaled
H370 Causes damage to organs
H373 May cause damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life

SECTION 3: Composition/information on ingredients


  • Product name: 2,4-Dinitrophenol
  • Synonyms: 2,4-dinitrophenol,2,4-DNP
  • CAS: 51-28-5
  • EC number: 200-087-7
  • MF: C6H4N2O5
  • MW: 184.11

SECTION 4: First aid measures

Description of first aid measures

General advice
First aider needs to protect himself. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Mixture with combustible ingredients.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Keep away from

heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains. Risk of explosion.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling

Work under hood. Do not inhale substance/mixture.

Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.

Light sensitive. Heat sensitive.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Body Protection

Flame retardant antistatic protective clothing.

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • AppearanceForm: crystalline Color: yellow
  • Odoursweet
  • Odour ThresholdNo data available d) pH 2,6 - 4,4 Melting point/freezing point Initial boiling point and boiling range Melting point/range: 108 - 112 °C - lit. No data available Flash point No data available Evaporation rate No data available Flammability (solid, The substance or mixture is a flammable solid with the category gas) 1. Upper/lower flammability or explosive limits No data available Vapour pressure 1,99 hPa at 18 °C Vapour density No data available Relative density 1,683 g/cm3 at 24 °C Water solubility 5,6 g/l at 18 °C - soluble Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: 1,54 No data available No data available Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available Explosive properties Explosive when dry. Oxidizing properties No data available
  • Melting point/freezing pointMelting point/range: 108 - 112 °C - lit.
  • Initial boiling point and boiling range108-112 °C (lit.)
  • Flash point318.03°C (rough estimate)
  • Evaporation rate11 °C
  • Flammability (solid, gas)The substance or mixture is a flammable solid with the category 1.
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure 1,99 hPa at 18 °C
  • Vapour density 39(x 10-5 mmHg) at 20 °C (Schwarzenbach et al., 1988)
  • Relative density1,683 g/cm3 at 24 °C
  • Water solubility5,6 g/l at 18 °C - soluble
  • Partition coefficient: n-octanol/waterlog Pow: 1,54
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesExplosive when dry.
  • Oxidizing propertiesNo data available
  • Henry's Law Constant5.70 x 10-8(atm?m3/mol) at 5 °C (average derived from six field experiments, Lüttke and Levsen, 1997)

Other safety information

Dissociation constant 4,09

SECTION 10: Stability and reactivity


The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Heat. Explosive when dry. no information available

Incompatible materials

Strong oxidizing agents, Strong bases, Acid chlorides, Acid anhydrides

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Mixture may cause damage to organs through prolonged or repeated exposure.
Aspiration hazard
No data available
LD50 (subcutaneous) for rats 25 mg/kg (quoted, RTECS, 1985).

SECTION 12: Ecological information



No data available

Persistence and degradability

No data available

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available



Toxicity to fish LC50 - Cyprinodon variegatus (sheepshead minnow) - 13,0 - 36,3 mg/l - 96,0 h

LC50 - Lepomis macrochirus (Bluegill) - 1,76 - 5,9 mg/l - 96,0 h

NOEC - Cyprinodon variegatus (sheepshead minnow) - 10,0 mg/l - 96,0 h

static test LC50 - Oncorhynchus mykiss (rainbow trout) - 0,39 mg/l - 96 h

Toxicity to daphnia and other aquatic invertebrates

EC50 - Daphnia magna (Water flea) - 6,10 - 7,00 mg/l - 24 h

LC50 - Daphnia magna (Water flea) - 4,1 mg/l - 48 h

Toxicity to algae EC50 - Desmodesmus subspicatus (green algae) - 40,00 mg/l - 48 h

EC50 - SELENASTRUM - 5,55 - 17,40 mg/l - 72 h

SECTION 13: Disposal considerations

Waste treatment methods


See for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 1320 IMDG: 1320 IATA: 1320

UN proper shipping name


IATA: Dinitrophenol, wetted


Transport hazard class(es)

ADR/RID: 4.1 (6.1) IMDG: 4.1 (6.1)

IATA: 4.1 (6.1)


Packaging group




Environmental hazards

ADR/RID: yes IMDG Marine pollutant: yes

IATA: no


Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Listed. website:
Measures for Environmental Management of New Chemical Substances
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website:
EC Inventory:Listed.
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website:
Korea Existing Chemicals List (KECL):Listed. website:
New Zealand Inventory of Chemicals (NZIoC):Listed. website:
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website:
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website:
Vietnam National Chemical Inventory:Listed. website:

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average


【1】CAMEO Chemicals, website:

【2】ChemIDplus, website:

【3】ECHA - European Chemicals Agency, website:

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:

【6】Germany GESTIS-database on hazard substance, website:

【7】HSDB - Hazardous Substances Data Bank, website:

【8】IARC - International Agency for Research on Cancer, website:

【9】IPCS - The International Chemical Safety Cards (ICSC), website:

【10】Sigma-Aldrich, website:

Other Information

Use all available methods for reducing body temperature.Because of its explosive properties, the compound is used in the form of a water paste.UN 0076 applies to the dry compound or wetted with less than 15% water (Hazard class 1, Subsidiary Risks 6.1). UN 1320 applies to compound wetted with no less than 15% waterCAS 25550-58-7 applies to unspecified isomers of dinitrophenol.

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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