Chemical Safety Data Sheet MSDS / SDS

2-CHLOROPHENYLZINC IODIDE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: 2-CHLOROPHENYLZINC IODIDE
CBnumber: CB1436675
CAS: 148651-35-8
Synonyms: 2-chlorophenylzinc iodide solution;2-Chlorophenylzinc iodide solution 0.5 in THF

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P403+P235 Store in a well-ventilated place. Keep cool.

P370+P378 In case of fire: Use … for extinction.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P405 Store locked up.

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire.

Hazard statements

H261 In contact with water releases flammable gas

H314 Causes severe skin burns and eye damage

H318 Causes serious eye damage

H333 May be harmful if inhaled

H225 Highly Flammable liquid and vapour

H302 Harmful if swallowed

H319 Causes serious eye irritation

H335 May cause respiratory irritation

H351 Suspected of causing cancer

SECTION 3: Composition/information on ingredients

Substance

Product name: 2-CHLOROPHENYLZINC IODIDE
Synonyms: 2-chlorophenylzinc iodide solution;2-Chlorophenylzinc iodide solution 0.5 in THF
CAS: 148651-35-8
MF: C6H4ClIZn
MW: 303.84

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture

Carbon oxides

5.3 Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.
Use water spray to cool unopened containers.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	3	Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
REACT	2	Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium)
SPEC. HAZ.	W

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.
For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet- brushing and place in container for disposal according to local regulations (see section 13).

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.

Advice on protection against fire and explosion

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

Hygiene measures

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Storage stabilityRecommended storage temperature

2 - 8 °C
Handle and store under inert gas. Hydrolyzes readily. Dry residue is explosive.

Storage class

Storage class (TRGS 510): 3: Flammable liquids

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis']	['Tetrahydrofuran', '109-99-9', 'PC-TWA', '300 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.']

Biological occupational exposure limits

['Component', 'CAS-No.', 'Parameters', 'Value', 'Biological\nspecimen', 'Basis']	['Tetrahydrofuran', '109-99-9', 'Tetrahydrof\nuran', '2 mg/l', 'Urine', 'ACGIH -\nBiological\nExposure Indices\n(BEI)']	['', 'Remarks', 'End of shift (As soon as possible after exposure ceases)', None, None, None]

8.2 Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

a) Physical stateliquid
b) ColorNo data available
c) OdorNo data available
d) Melting point/freezing pointNo data available
e) Initial boiling point and boiling rangeNo data available
f) Flammability (solid, gas)No data available
g) Upper/lower flammability or explosive limitsNo data available
h) Flash point-17.22 °C - closed cup
i) Autoignition temperatureNo data available
j) Decomposition temperatureNo data available
k) pHNo data available
l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubilityNo data available
n) Partition coefficient n-octanol/waterNo data available
o) Vapor pressureNo data available
p) Density1.066 g/cm3
Relative density0.973 g/mL at 25 °C
q) Relative vapor densityNo data available
r) Particle characteristicsNo data available
s) Explosive propertiesNot classified as explosive.
t) Oxidizing propertiesnone

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Chemical stability

Stable under recommended storage conditions.

10.2 Possibility of hazardous reactions

No data available

10.3 Conditions to avoid

Heat, flames and sparks. Extremes of temperature and direct sunlight.

10.4 Incompatible materials

Oxidizing agents, Oxygen

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity

Oral: No data available
Inhalation: No data available
Acute toxicity estimate Dermal - 2,500 mg/kg (Calculation method)

Skin corrosion/irritation

Classified based on available data. For more details, see section 2

Serious eye damage/eye irritation

Classified based on available data. For more details, see section 2

Respiratory or skin sensitization

Classified based on available data. For more details, see section 2

Germ cell mutagenicity

Classified based on available data. For more details, see section 2

Carcinogenicity

Classified based on available data. For more details, see section 2

Reproductive toxicity

Classified based on available data. For more details, see section 2

Specific target organ toxicity - single exposure

Classified based on available data. For more details, see section 2

Specific target organ toxicity - repeated exposure

Classified based on available data. For more details, see section 2

Aspiration hazard

Classified based on available data. For more details, see section 2

11.2 Additional Information

Central nervous system depression, Cough, chest pain, Difficulty in breathing, Exposure to high airborne concentrations can cause anesthetic effects., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Components Tetrahydrofuran

Acute toxicity

LD50 Oral - Rat - male and female - 1,650 mg/kg
Remarks: (ECHA)
Symptoms: Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 6 h - > 14.7 mg/l - vapor (US-EPA)
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)

Skin corrosion/irritation

Skin - Rabbit
Result: No skin irritation - 72 h (Draize Test)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.

Serious eye damage/eye irritation

Eyes - Rabbit
Result: Causes serious eye irritation.
Remarks: (IUCLID)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)

Respiratory or skin sensitization

Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)

Germ cell mutagenicity

Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Red blood cells (erythrocytes)
Result: negative

Carcinogenicity

Suspected of causing cancer.

Reproductive toxicity

Classified based on available data. For more details, see section 2

Specific target organ toxicity - single exposure

Inhalation - May cause respiratory irritation. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause drowsiness or dizziness.
Acute oral toxicity - Irritation of mucous membranes

Specific target organ toxicity - repeated exposure Aspiration hazard

Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

12.1 Toxicity

Mixture

No data available

12.2 Persistence and degradability

No data available

12.3 Bioaccumulative potential

No data available

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Endocrine disrupting properties

No data available

12.7 Other adverse effects

No data available

Components Tetrahydrofuran

Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 2,160 mg/l - 96 h (OECD Test Guideline 203)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 3,485 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to flow-through test NOEC - Pimephales promelas (fathead fish(Chronic toxicity) minnow) - 216 mg/l - 33 d
Remarks: (ECHA)

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

14.1 UN number

ADR/RID: 2056
IMDG: 2056
IATA-DGR: 2056

14.2 UN proper shipping name

ADR/RID: TETRAHYDROFURAN,SOLUTION
IMDG: TETRAHYDROFURAN,SOLUTION
IATA-DGR: Tetrahydrofuran,SOLUTION

14.3 Transport hazard class(es)

ADR/RID: 3
IMDG: 3
IATA-DGR: 3

14.4 Packaging group

ADR/RID: II
IMDG: II
IATA-DGR: II

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no

14.6 Special precautions for user

Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.

14.7 Incompatible materials

Oxidizing agents, Oxygen

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification number : B1A222231920
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.