3-Hydroxy-2-naphthoic acid
Product identifier
- Product name: 3-Hydroxy-2-naphthoic acid
- CBnumber: CB4334794
- CAS: 92-70-6
- EINECS Number: 202-180-8
- Synonyms: 3-hydroxy-2-naphthoic acid,Bon acid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Serious eye damage, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
Label elements
Pictogram(s)
- Signal wordWarning
H301 Toxic if swalloed
H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child
H371 May cause damage to organs
H412 Harmful to aquatic life with long lasting effects
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 3-Hydroxy-2-naphthoic acid
- Synonyms: 3-hydroxy-2-naphthoic acid,Bon acid
- CAS: 92-70-6
- EC number: 202-180-8
- MF: C11H8O3
- MW: 188.18
Description of first aid measures
If inhaledFresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Seek medical attention if you feel unwell.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool . Cover skin burns with dry sterile dressings after decontamination . Poison A and B
Extinguishing media
Use water spray, foam, dry powder.
Specific Hazards Arising from the Chemical
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Advice for firefighters
Use water spray, foam, dry powder.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Environmental precautions
Personal protection: . Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
Methods and materials for containment and cleaning up
Waste water treatment: ion exchange: adsorption on Amberlite XAD-2: 39% retention, influent: 0.6 ppm.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong oxidants. Store in an area without drain or sewer access.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateFine Crystalline Powder
- ColourYellow to beige-brown
- Odour
no data available
- Melting point/freezing point
217 °C. Atm. press.:Ca. 1 atm. Remarks:Exothermic decomposition from 320°C (in sealed vial ), process still incomplete at 450°C.
- Boiling point or initial boiling point and boiling range
122°C(lit.)
- Flammability
Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
85°C(lit.)
- Auto-ignition temperature
> 440 °C. Atm. press.:Ca. 1 atm. Remarks:Pure substance.;> 220 °C. Atm. press.:Ca. 1 atm. Remarks:1:1 mixture with kieselgur.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility0.072g/l practically insoluble
- Partition coefficient n-octanol/water
log Pow = 1.44. Temperature:23 °C.
- Vapour pressure
< 0.1 Pa. Temperature:20 °C. Remarks:Determined by calculation.
- Density and/or relative density
1.428 g/cm3. Temperature:23 °C.
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
Decomposes on heating. This produces irritating fumes. Reacts with strong oxidants.
Chemical stability
no data available
Possibility of hazardous reactions
No data.Decomposes on heating. This produces irritating fumes. Reacts with strong oxidants.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
Acute toxicity
- Oral: LD50 - rat (male/female) - 823 mg/kg bw.
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is severely irritating to the eyes. The substance is irritating to the skin.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the kidneys, liver and endocrine system.
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached.
Toxicity
- Toxicity to fish: LC50 - Danio rerio (previous name: Brachydanio rerio) - 68 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 106 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 65.3 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge, domestic - 2 171 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
The biodegradability of org substances in wastewater by activated-sludge was determined. beta-hydroxynaphthoic acid was resistant to degradation.
Bioaccumulative potential
The BCF values of 3-hydroxy-2-naphthalenecarboxylic acid at water concentrations of 0.1 and 1.0 mg/l were 6.7 or lower, measured in carp over an 6 week exposure period(1). According to a classification scheme(2), these BCF values suggest the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of 3-hydroxy-2-naphthalenecarboxylic acid is estimated as 1,100(SRC), using a measured log Kow of 3.05(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 3-hydroxy-2-naphthalenecarboxylic acid is expected to have low mobility in soil. The pKa of 3-hydroxy-2-naphthalenecarboxylic acid is 2.79(4), indicating that this compound will exist as an anion in moist soils(SRC) and the mobility of anions is usually much greater than neutral species(5).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Health effects of exposure to the substance have not been investigated adequately.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.