Chemical Safety Data Sheet MSDS / SDS
4-Ethylphenol
Revision Date:2026-03-22Revision Number:1
Product identifier
- Product name: 4-Ethylphenol
- CBnumber: CB2106353
- CAS: 123-07-9
- EINECS Number: 204-598-6
- Synonyms: Phenol,4-ethyl- ;P-ETHYLPHENOL
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H318 Causes serious eye damage
Substance
- Product name: 4-Ethylphenol
- Synonyms: 4-Ethylphenol,PEP
- CAS: 123-07-9
- EC number: 204-598-6
- MF: C8H10O
- MW: 122.16
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Carbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.
Hazardous combustion products
Carbon oxides
Specific extinguishing methods
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
In the event of fire, wear self-contained breathing apparatus.
NFPA 704
1
0
| HEALTH | |||
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Handling
For precautions see section 2.2.
Storage
Further information on storage conditionsTightly closed. Dry.
Storage class
11, Combustible Solids
Recommended storage temperature
Recommended storage temperature see product label.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type P2
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
protective clothing
Hand protection
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Full contact
Manufacturer
KCL 741 L
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Splash contact
Manufacturer
KCL 741 L
Remarks
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D- 36124 Eichenzell, Internet: www.kcl.de).
Hygiene measures
Change contaminated clothing. Wash hands after working with substance.
Information on basic physicochemical properties
- Solubility4.9g/l
- Physical stateCrystalline Mass or Crystals
- AppearanceSolidified mass or fragments
- Coloryellow beige
- Odorwoody, phenol-like, sweet
- Odor ThresholdNo data available
- pHNo data available
- pH4
Method: OECD Test Guideline 105
GLP: yes - pH7
Method: OECD Test Guideline 117
GLP: yes Bioaccumulation is not expected. - Melting point/ range41 - 44 °C 40 - 42 °C
Method: lit. - Boiling point/boiling range218 - 219 °C
Method: lit. - Flash point100 °C
Method: closed cup - Evaporation rateNo data available
- Burning rateNo data available
Self-ignition : Method: Relative self-ignition temperature for solids
GLP: yes does not ignite - Upper explosion limit / Upper flammability limitNo data available
- Lower explosion limit / Lower flammability limitNo data available
- Vapor pressure0.17 hPa (20 °C)
- Relative vapor density4.22
- Relative density1.06 (20 °C)
Method: OECD Test Guideline 109
GLP: yes - Density1.01 g/cm3 (20 °C)
- Water solubility7.4 g/l soluble (20 °C)
- Partition coefficient: n-octanol/waterlog Pow: 2.1 (20 °C)
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- Viscosity, dynamicNo data available
- Viscosity, kinematicNo data available
- Flow timeNo data available
Explosive properties : Method: Explosive properties
GLP: yes Not classified as explosive.
Oxidizing properties : Method: Regulation (EC) No. 440/2008, Annex, A.17
GLP: yes none - Surface tension54 mN/m, 998 g/l, 22 °C, OECD Test Guideline 115,
GLP: yes - Molecular weight122.16 g/mol
Reactivity
Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Violent reactions possible with: Acid anhydrides acid halides Oxidizing agents
Conditions to avoid
Strong heating.
Incompatible materials
No data available
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 401)
Inhalation: Irritating to respiratory system.
LD50 Dermal - Rabbit - > 5,000 mg/kg
Remarks: (ECHA)
LD50 Dermal - Rat - > 5,000 mg/kg
Remarks: (HSDB)
Skin corrosion/irritation
Inhalation: Irritating to respiratory system.
LD50 Dermal - Rabbit - > 5,000 mg/kg
Remarks: (ECHA)
LD50 Dermal - Rat - > 5,000 mg/kg
Remarks: (HSDB)
Skin - Rabbit
Result: No eye irritation - 24 h
Remarks: (ECHA)
Serious eye damage/eye irritation
Result: No eye irritation - 24 h
Remarks: (ECHA)
Eyes - Rabbit
Result: Risk of serious damage to eyes.
Remarks: (ECHA)
Respiratory or skin sensitization
Result: Risk of serious damage to eyes.
Remarks: (ECHA)
Draize Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 406)
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Human lymphocytes
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Carcinogenicity
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Human lymphocytes
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: SL4040000
Depending on the intensity and duration of exposure, effects may vary from mild irritation to severe destruction of tissue., prolonged or repeated exposure can cause:, Damage to the eyes.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Depending on the intensity and duration of exposure, effects may vary from mild irritation to severe destruction of tissue., prolonged or repeated exposure can cause:, Damage to the eyes.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Ecotoxicity
Components:
p-Hydroxyethylbenzene:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 10.4 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 203
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 9 mg/l End point: Immobilization Exposure time: 48 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes
Toxicity to algae/aquatic plants
ErC50 (Pseudokirchneriella subcapitata): > 22 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: OECD Test Guideline 201 GLP: yes
Persistence and degradability
Components:
p-Hydroxyethylbenzene:
Biodegradabilityaerobic Inoculum: activated sludge Result: Readily biodegradable. Biodegradation: 87 % Exposure time: 28 d Method: OECD Test Guideline 310 GLP: yes
Bioaccumulative potential
Components:
p-Hydroxyethylbenzene:
Partition coefficient: noctanol/waterlog Pow: 2.1 (20 °C) pH: 7 Method: OECD Test Guideline 117 GLP: yes Remarks: Bioaccumulation is not expected.
Mobility in soil
No data available
Other adverse effects
Components:
p-Hydroxyethylbenzene:
Additional ecological informationDischarge into the environment must be avoided.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : Not applicable
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
Packing instruction (cargo aircraft) : Not applicable
Packing instruction (passenger aircraft) : Not applicable
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
Packing instruction (cargo aircraft) : Not applicable
Packing instruction (passenger aircraft) : Not applicable
IMDG-Code
UN number : Not applicable
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
EmS Code : Not applicable
Marine pollutant : no
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
EmS Code : Not applicable
Marine pollutant : no
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
Domestic regulation GB 6944/12268
UN number : Not applicable
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
Domestic regulation GB 6944/12268
UN number : Not applicable
Proper shipping name : Not applicable
Class : Not applicable
Subsidiary risk : Not applicable
Packing group : Not applicable
Labels : Not applicable
Special precautions for user
Remarks : Not classified as dangerous in the meaning of transport regulations.
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
applicable
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
Not listed
Hazardous Chemicals for Priority Management
Not listed under SAWS
Regulations on Occupational Labor Protection in the at workplaces where
Toxic Substances Are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Full text of other abbreviations
AIIC - Australian Inventory of Industrial Chemicals
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonized System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organization
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC -No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organization for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonized System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organization
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC -No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organization for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.