ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

4,6-DIMETHOXYINDOLE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 4,6-DIMETHOXYINDOLE
  • CBnumber: CB7407019
  • CAS: 23659-87-2
  • Synonyms: AKOS JY2083231;4,6-DIMETHOXY-1H-INDOLE

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordWarning
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 4,6-DIMETHOXYINDOLE
  • Synonyms: AKOS JY2083231;4,6-DIMETHOXY-1H-INDOLE
  • CAS: 23659-87-2
  • MF: C10H11NO2
  • MW: 177.2

SECTION 4: First aid measures

First Aid Measures

General advice
If symptoms persist, call a physician. Do not breathe dust/fume/gas/mist/vapors/spray. Do not get in eyes, on skin, or on clothing.
Eye contact
Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. If symptoms persist, call a physician.
Skin Contact
Consult a physician if necessary. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Wash contaminated clothing before reuse.
Wash off immediately with plenty of water. If skin irritation persists, call a physician.
Immediate medical attention is not required.
Inhalation
Remove to fresh air Call a physician If breathing is irregular or stopped, administer artificial respiration Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation
Artificial respiration and/or oxygen may be necessary Immediate medical attention is not required Move to fresh air in case of accidental inhalation of vapors If symptoms persist, call a physician
Ingestion
Rinse mouth. Drink plenty of water. If symptoms persist, call a physician. Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Call a physician.
Self-protection of the first aider
Use personal protective equipment as required.

Most important symptoms and effects, both acute and delayed

Symptoms
No information available.

Indication of any immediate medical attention and special treatment needed

Note to physicians
Treat symptomatically.

SECTION 5: Firefighting measures

Suitable Extinguishing Media

Suitable Extinguishing Media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.

Specific hazards arising from the chemical

Specific hazards arising from the chemical
No information available.
Hazardous combustion products
Carbon oxides.

Explosion data

Sensitivity to Mechanical Impact
No information available.
Sensitivity to Static Discharge
No information available.

Protective equipment and precautions for firefighters

Protective equipment and precautions for firefighters
As in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal precautions
Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak.

Environmental precautions

Environmental precautions
Prevent entry into waterways, sewers, basements or confined areas. Do not flush into surface water or sanitary sewer system. Prevent further leakage or spillage if safe to do so.
Prevent product from entering drains. See Section 12 for additional Ecological Information.

Methods and material for containment and cleaning up

Methods for containment
Prevent further leakage or spillage if safe to do so.
Methods for cleaning up
Use personal protective equipment as required. Take up mechanically, placing in appropriate containers for disposal. Clean contaminated surface thoroughly. Cover powde spill with plastic sheet or tarp to minimize spreading and keep powder dry. Avoid creating dust. Soak up with inert absorbent material. Dam up. Pick up and transfer to properly labeled containers. Sweep up and shovel into suitable containers for disposal. Afte cleaning, flush away traces with water. Take precautionary measures against static discharges.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Use with local exhaust ventilation.

Conditions for safe storage, including any incompatibilities

Storage Conditions
Keep container tightly closed in a dry and well-ventilated place. Keep out of the reach of children. Keep containers tightly closed in a cool, well-ventilated place. Keep in properly labeled containers. Store at room temperature.
Incompatible materials
None known based on information supplied.

SECTION 8: Exposure controls/personal protection

Control parameters

Exposure Guidelines
This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.

Appropriate engineering controls

Engineering Controls
Showers
Eyewash stations
Ventilation systems

Individual protection measures, such as personal protective equipment

Eye/face protection
Tight sealing safety goggles. Face protection shield.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Physical StateSolid
  • AppearanceOff-white to light brown Solid
  • OdorNo information available
  • pHNo information available
  • Melting point/freezing point122 °C
  • Boiling point343.8 °C
  • Flash point125.7 °C
  • Liquid Density1.2 g/cm3
  • Evaporation rateNo information available
  • Upper flammability limitsNo information available
  • Lower flammability limitNo information available
  • Vapor pressureNo information available
  • Vapor densityNo information available
  • Specific gravityNo information available
  • Water solubilityNo information available
  • Solubility in other solventsNo information available
  • Partition coefficient2.22
  • Autoignition temperatureNo information available
  • Decomposition temperatureNo information available
  • Kinematic viscosityNo information available
  • Explosive propertiesNo information available
  • Oxidizing propertiesNo information available
  • Density and/or relative density1.182±0.06 g/cm3(Predicted)

SECTION 10: Stability and reactivity

Reactivity

Not applicable

Chemical stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing.

Hazardous polymerization

No information available.

Conditions to avoid

Extremes of temperature and direct sunlight.

Incompatible materials

Strong oxidizing agents.

Hazardous Decomposition Products

Carbon oxides.

SECTION 11: Toxicological information

Information on likely routes of exposure

Inhalation
Classified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.

Information on toxicological effects

Symptoms
Classified based on available data. For more details, see section 2.

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Chronic Toxicity
Avoid repeated exposure.

Numerical measures of toxicity - Product Information

Unknown acute toxicity
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

Ecotoxicity

May cause long lasting harmful effects to aquatic life
100% of the mixture consists of components(s) of unknown hazards to the aquatic environment.

Persistence and degradability

No information available.

Bioaccumulation

No information available.

Mobility

No information available.

SECTION 13: Disposal considerations

Disposal of wastes

Disposal should be in accordance with applicable regional, national and local laws and regulations.

Contaminated packaging

Do not reuse container.

Other Information

Waste codes should be assigned by the user based on the application for which the product was used.

SECTION 14: Transport information

DOT

Not regulated

IMDG

Not regulated

IATA

Not regulated

SECTION 15: Regulatory information

International Inventories

All of the components in the product are on the following Inventory lists
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances

US Federal Regulations

SARA 313

Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

SARA 311/312 Hazard Categories

Acute health hazard
Yes
Chronic Health Hazard
No
Fire hazard
No
Sudden release of pressure hazard
No
Reactive hazard
No

CWA (Clean Water Act)

This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).

US State Regulations

California Proposition 65

This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

This product does not contain any substances regulated by state right-to-know regulations

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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