Chemical Safety Data Sheet MSDS / SDS

LITHIUM B-ISOPINOCAMPHEYL-9-BORABICYCLO[3.3.1]NONYL HYDRIDE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: LITHIUM B-ISOPINOCAMPHEYL-9-BORABICYCLO[3.3.1]NONYL HYDRIDE
  • CBnumber: CB2182793
  • CAS: 64081-12-5
  • Synonyms: alpine hydride;R-alpine-hydride

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P403+P235 Store in a well-ventilated place. Keep cool.
P402+P404 Store in a dry place. Store in a closed container.
P370+P378 In case of fire: Use … for extinction.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P231+P232 Handle under inert gas. Protect from moisture.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H351 Suspected of causing cancer
H335 May cause respiratory irritation
H314 Causes severe skin burns and eye damage
H260 In contact with water releases flammable gases which may ignite spontaneously
H225 Highly Flammable liquid and vapour

SECTION 3: Composition/information on ingredients

Substance

  • Product name: LITHIUM B-ISOPINOCAMPHEYL-9-BORABICYCLO[3.3.1]NONYL HYDRIDE
  • Synonyms: alpine hydride;R-alpine-hydride
  • CAS: 64081-12-5
  • MF: C18H32BLi
  • MW: 266.2

SECTION 4: First aid measures

General advice

First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Call in physician.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

In case of eye contact

After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

Water Foam

Specific hazards during fire fighting

Combustible. Pay attention to flashback. Vapors are heavier than air and may spread along floors. May not get in touch with: Water Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.

Hazardous combustion products

Carbon oxides Borane/boron oxides Lithium oxides

Specific extinguishing methods

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains. Risk of explosion.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols. Keep workplace dry. Do not allow product to come into contact with water.
Avoidance of contact
Water Alcohols Oxidizing agents Oxygen

Storage

Further information on storage conditions
Tightly closed. Keep away from heat and sources of ignition.
Materials to avoid
Never allow product to get in contact with water during storage.
Storage class
4.3, Hazardous materials, which set free flammable gases upon contact with water
Recommended storage temperature
Recommended storage temperature see product label.
Further information on storage stability
Store under inert gas. Air and moisture sensitive. Reacts violently with water. Test for peroxide formation periodically and before distillation.

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Biological occupational exposure limits drofuran shift BEI (As soon as possible after exposure ceases)

Engineering measures

No data available

Personal protective equipment

Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Flame retardant antistatic protective clothing.
Hand protection
Remarks
required
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Particle characteristics Particle sizeNo data available
  • Molecular weight266.20 g/mol
  • Oxidizing propertiesnone
  • Explosive propertiesNot classified as explosive.
  • Flow timeNo data available
  • Viscosity, kinematicNo data available
  • Viscosity, dynamicNo data available
  • Decomposition temperatureNo data available
  • Autoignition temperatureNo data available
  • Partition coefficient: n-octanol/waterNo data available
  • Water solubilityNo data available
  • Density0.919 g/cm3 (25 °C)
    Method: lit.
  • Relative density0.919 g/mL at 25 °C(lit.)
  • Relative vapor densityNo data available
  • Vapor pressureNo data available
  • Lower explosion limit / Lower flammability limitNo data available
  • Upper explosion limit / Upper flammability limitNo data available
  • Burning rateNo data available
  • Flammability (liquids)No data available
  • Flammability (solid, gas)No data available
  • Evaporation rateNo data available
  • Flash point-17 °C
  • Boiling point/boiling rangeNo data available
  • Melting point/ rangeNo data available
  • pHNo data available
  • Odor ThresholdNo data available
  • OdorNo data available
  • ColorNo data available
  • Appearanceliquid
  • Physical stateliquid

SECTION 10: Stability and reactivity

Reactivity

Formation of peroxides possible. Vapors may form explosive mixture with air.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Warming. Moisture.

Incompatible materials

Water Alcohols Oxidizing agents Oxygen

Hazardous decomposition products

Peroxides : In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Oral: No data available
Acute toxicity estimate Oral - 1,238 mg/kg (Calculation method)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Acute toxicity estimate Inhalation - 4 h - > 10 mg/l - dust/mist(Calculation meth- od)
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
Acute toxicity estimate Dermal - > 5,000 mg/kg (Calculation method)
Skin corrosion/irritation
Remarks: Mixture causes burns.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye damage.
Risk of blindness!
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Evidence of a carcinogenic effect.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause respiratory irritation.
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, in- flammation and edema of the larynx, spasm, inflammation and edema of the bron- chi, pneumonitis, pulmonary edema, Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Central nerv- ous system depression, chest pain, Difficulty in breathing, Exposure to high air- borne concentrations can cause anesthetic effects.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Tetrahydrofuran
Acute toxicity
LD50 Oral - Rat - male and female - 1,650 mg/kg
Remarks: (ECHA)
Symptoms: Irritation of mucous membranes
LC50 Inhalation - Rat - male and female - 6 h - > 14.7 mg/l - vapor (US-EPA)
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 72 h (Draize Test)
Remarks: Repeated or prolonged exposure may cause skin irritation and dermatitis, due to degreasing properties of the product.
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
Remarks: (IUCLID)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female - Red blood cells (erythrocytes)
Result: negative
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause drowsiness or dizziness.
Acute oral toxicity - Irritation of mucous membranes
Specific target organ toxicity - repeated exposure Aspiration hazard
Classified based on available data. For more details, see section 2
Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride
Acute toxicity
Oral: No data available
LC50 Inhalation - 4 h - 1.5 mg/l - dust/mist (Acute toxicity estimate)
LD50 Dermal - 1,100 mg/kg
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

Ecotoxicity

Components:

Tetrahydrofuran:

Toxicity to fish
LC50 (Pimephales promelas (fathead minnow)): 2,160 mg/l End point: mortality Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 203
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 3,485 mg/l End point: mortality Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202
Toxicity to fish (Chronic toxicity)
NOEC (Pimephales promelas (fathead minnow)): 216 mg/l End point: Growth inhibition Exposure time: 33 d Test Type: flow-through test Analytical monitoring: yes Remarks: (ECHA)

Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride:

Toxicity to fish
Remarks: No data available

Persistence and degradability

Components:

Tetrahydrofuran:

Biodegradability
aerobic Inoculum: activated sludge Concentration: 2 mg/l Biochemical oxygen demand Result: Not readily biodegradable. Biodegradation: 39 % Exposure time: 28 d Method: OECD Test Guideline 301D

Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride:

Biodegradability
Remarks: No data available

Bioaccumulative potential

Components:

Tetrahydrofuran:

Partition coefficient: noctanol/water
log Pow: 0.45 (25 °C) Method: OECD Test Guideline 107 Remarks: Bioaccumulation is not expected.

Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride:

Bioaccumulation
Remarks: No data available

Mobility in soil

Components:

Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride:

Stability in soil
Remarks: No data available

Other adverse effects

Components:

Tetrahydrofuran:

Results of PBT and vPvB assessment
Substance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.

Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride:

Additional ecological information
No data available

SECTION 13: Disposal considerations

Disposal methods

Waste from residues
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

International Regulations

IATA-DGR

UN/ID No. : UN 3399
Proper shipping name : Organometallic substance, liquid, water-reactive, flammable (Lithium B-isopinocampheyl-9borabicyclo[3.3.1]nonyl hydride, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : I
Labels : Division 4.3 - Substances which in contact with water emit flammable gases, Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 494
Packing instruction (passenger aircraft) : Not permitted for transport

IMDG-Code

UN number : UN 3399
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Lithium B-isopinocampheyl-9-borabicyclo[3.3.1]nonyl hydride, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : I
Labels : 4.3 (3)
EmS Code : F-G, S-N
Marine pollutant : no

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Not applicable for product as supplied.
National regulation

JT/T 617

UN number : UN 3399
Proper shipping name : ORGANOMETALLIC SUBSTANCE, LIQUID, WATERREACTIVE, FLAMMABLE (Lithium B-isopinocampheyl-9borabicyclo[3.3.1]nonyl hydride, Tetrahydrofuran)
Class : 4.3
Subsidiary risk : 3
Packing group : I
Labels : 4.3 (3)
Environmentally hazardous : no

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15: Regulatory information

Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.

National regulatory information

Law on the Prevention and Control of Occupational Diseases

Regulations on Safety Management of Hazardous Chemicals

Catalogue of Hazardous Chemicals

Listed

Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)

No. / Code Chemical name / Category Threshold quantity

W5.3 Flammable liquids 1,000 t

W11 Substances and mixtures which in 200 t contact with water, emit flammable gases

Hazardous Chemicals for Priority Management

Not listed under SAWS

Catalogue of Specially Controlled Hazardous

Not listed Chemicals

List of Explosive Precursors

Not listed

Regulations on Occupational Labor Protection in the at workplaces where

Toxic Substances Are Used

Catalogue of Highly Toxic Chemicals

Not listed

Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals

China Severely Restricted Toxic Chemicals for Import and Export

Not listed

Measures on the Environmental Administration of New Chemical Substances Registration

Registration/Notification number

B1A222232947

Regulation on the Administration of Precursor Chemicals

Catalogue and Classification of Precursor Chemicals

Not listed

Regulations on the Administration of Controlled Chemicals

List of Controlled Chemicals

Not listed

Regulations of Ozone Depleting Substances Management

List of Controlled Ozone Depleting Substances

Not listed

List of Controlled Ozone Depleting Substances Import and Export

Not listed

Environmental Protection Law

List of Priority Controlled Chemicals

Not listed

List of Key Controlled New Pollutants

Not listed

SECTION 16: Other information

Full text of other abbreviations

ACGIH
USA. ACGIH Threshold Limit Values (TLV)
ACGIH BEI
ACGIH - Biological Exposure Indices (BEI)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
ACGIH / STEL
Short-term exposure limit
GBZ 2.1-2007 / PC-TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - time weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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