Chemical Safety Data Sheet MSDS / SDS

Polyethylene Glycol

Revision Date:2026-03-22Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: Polyethylene Glycol
CBnumber: CB6145866
CAS: 25322-68-3
EINECS Number: 500-038-2
Synonyms: PEG;PEG 400

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P501 Dispose of contents/container to..…

P391 Collect spillage. Hazardous to the aquatic environment

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P273 Avoid release to the environment.

Hazard statements

H302 Harmful if swallowed

H311 Toxic in contact with skin

H411 Toxic to aquatic life with long lasting effects

H373 May cause damage to organs through prolonged or repeated exposure

SECTION 3: Composition/information on ingredients

Substance

Product name: Polyethylene Glycol
Synonyms: PEG,Polyethylene Glycol
CAS: 25322-68-3
EC number: 500-038-2
MF: (C2H4O)nH2O
MW: 0

SECTION 4: First aid measures

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all con- taminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

Nature of decomposition products not known.

Specific extinguishing methods

Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipbreathing ment for fire-fighters

In the event of fire, wear self-contained apparatus.

NFPA 704

HEALTH	0	Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials
FIRE	1	Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Avoidance of contact

Strong acids Strong bases Strong oxidizing agents

Storage

Further information on storage conditions

Tightly closed.

Storage class

10, Combustible liquids

Recommended storage temperature

2 - 8 °C

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

Engineering measures

No data available

Personal protective equipment

Respiratory protection

Not required; except in case of aerosol formation.

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses

Hand protection

Remarks

not required

Hygiene measures

Change contaminated clothing. Wash hands after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

SolubilityH₂O: 50 mg/mL, clear, colorless
Physical statewaxy solid
Absorption≤0.1 at 280nm
≤0.2 at 260nm
Viscosity1,650-3,850cp (1% solution @ 25C)
Viscosity11cs (99C)
Viscosity4.5cs (99C)
Viscosity5,500-8,000cp (1% solution @ 25C)
Viscosity6cs (99C)
Viscosity7.4cs (99C)
Viscosity750cp (5% solution @ 25C)
Viscosity75cp (5% solution @ 25C)
Viscosity8,000cs (99C)
Viscosity8,800-17,600cp (5% solution @ 25C)
Viscosity93cs (99C)
Particle characteristics Particle sizeNo data available
Oxidizing propertiesnone
Explosive propertiesNo data available
Flow timeNo data available
Viscosity, kinematicNo data available
Viscosity, dynamicNo data available
Decomposition temperatureNo data available
Autoignition temperatureNo data available
Evaporation rateNo data available
Flash point138.6 °C (976.4 hPa)
Method: closed cup
Boiling point/boiling range205.7 °C (977.6 hPa)
Method: OECD Test Guideline 103
Melting point/ range57.5 °C
pH5.5-7.0 (25℃, 50mg/mL in H2O)
Odor ThresholdNo data available
OdorNo data available
Colorlight yellow
Appearanceliquid (20 °C , 1,013 hPa)
Bioaccumulation is not expected.
Partition coefficient: n-octanol/waterlog Pow: -0.698 (30 °C)
Water solubility256.084 g/l completely soluble (25 °C)
Method: OECD Test Guideline 105
Density1.116 g/cm3 (20 °C, 975.5 hPa)
Method: OECD Test Guideline 109
Relative density1.27 g/mL at 25 °C
Relative vapor density>1 (vs air)
Vapor pressure< 0.01 hPa (20 °C)
Lower explosion limit / Lower flammability limitNo data available
Upper explosion limit / Upper flammability limitNo data available
Self-ignition360 °C
Burning rateNo data available
Flammability (liquids)No data available
Flammability (solid, gas)No data available

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous

No data available reactions

Conditions to avoid

Strong heating.

Incompatible materials

Strong acids Strong bases Strong oxidizing agents

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - female - > 2,000 mg/kg (OECD Test Guideline 423)
Inhalation: No data available
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)

Skin corrosion/irritation

Skin - Rabbit
Result: No skin irritation - 72 h (OECD Test Guideline 404)

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation - 24 h (OECD Test Guideline 405)

Respiratory or skin sensitization

Maximization Test - Guinea pig
Result: Not a skin sensitizer.
Remarks: (Lit.) (ECHA)

Germ cell mutagenicity

Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative

Carcinogenicity