Chemical Safety Data Sheet MSDS / SDS

β-Alanine

Revision Date:2024-07-13Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: β-Alanine
  • CBnumber: CB0711205
  • CAS: 107-95-9
  • EINECS Number: 203-536-5
  • Synonyms: Beta-Alanine,3-aminopropanoic acid

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Signal wordWarning
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: β-Alanine
  • Synonyms: Beta-Alanine,3-aminopropanoic acid
  • CAS: 107-95-9
  • EC number: 203-536-5
  • MF: C3 H7 N O2
  • MW: 89.09

SECTION 4: First aid measures

Description of first aid measures

If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

Notes to physician

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx) Combustible.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

1
0
0
HEALTH 1 Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride)
FIRE 0 Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Tightly closed. Dry.

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

Change contaminated clothing. Wash hands after working with substance.

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0.11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0.11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L


Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.


Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearance crystals
  • OdourNo data available
  • Odour ThresholdNo data available d) pH 6.0 - 7.5 Melting point/freezing point Initial boiling point and boiling range Melting point/range: 202 °C - dec. No data available Flash point Not applicable Evaporation rate No data available Flammability (solid, No data available gas) Upper/lower flammability or explosive limits No data available Vapour pressure No data available Vapour density No data available Relative density 1.437 g/cm3 at 19 °C Water solubility 89.09 g/l at 20 °C Partition coefficient: n-octanol/water Autoignition temperature Decomposition temperature log Pow: -3.05 - Bioaccumulation is not expected. not auto-flammable No data available Viscosity No data available Explosive properties No data available Oxidizing properties No data available
  • Melting point/freezing pointMelting point/range: 202 °C - dec.
  • Initial boiling point and boiling range202 °C (dec.)(lit.)
  • Flash pointNot applicable
  • Evaporation rate204-206°C
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limitsNo data available
  • Vapour pressure No data available
  • Vapour density No data available
  • Relative density1.437 g/cm3 at 19 °C
  • Water solubility89.09 g/l at 20 °C
  • Partition coefficient: n-octanol/waterlog Pow: -3.05 - Bioaccumulation is not expected.
  • Autoignition temperaturenot auto-flammable
  • Decomposition temperatureNo data available
  • Viscosity204-206 ºC
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available
  • λmaxλ: 260 nm Amax: ≤0.02
    λ: 280 nm Amax: ≤0.02

Other safety information

No data available

SECTION 10: Stability and reactivity

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

no information available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx)

Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - male and female - > 5,000 mg/kg Remarks: (ECHA)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
(OECD Test Guideline 429)
Germ cell mutagenicity
Ames test
Escherichia coli/Salmonella typhimurium Result: negative
Chromosome aberration test in vitro Chinese hamster fibroblasts
Result: negative
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose toxicity - Rat - male and female - Gavage - 28 d - NOAEL (No observed adverse effect level) - 1,000 mg/kg
RTECS: UA2369200
This substance is a cholinoreceptor antagonist at the neuromuscular junction. This substance posses curare-like properties and should be handled with extreme care.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
This is a non-essential amino acid that occurs in many forms in natural protein.
No toxic effects are to be expected when the product is handled appropriately. Handle in accordance with good industrial hygiene and safety practice.

SECTION 12: Ecological information

Toxicity

Toxicity to fish
semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96 h

(OECD Test Guideline 203)

Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h

and other aquatic invertebrates

(OECD Test Guideline 202)

Toxicity to algae
static test ErC50 - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h

(OECD Test Guideline 201)

Persistence and degradability

Biodegradability aerobic - Exposure time 14 d

Result: 87 % - Readily biodegradable. (OECD Test Guideline 301C)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company.


SECTION 14: Transport information

UN number

ADR/RID: - IMDG: - IATA-DGR: -

UN proper shipping name

ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA-DGR: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA-DGR: -

Packaging group

ADR/RID: - IMDG: - IATA-DGR: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA-DGR: no

Special precautions for user

Incompatible materials

Strong oxidizing agents

Further information

Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
EC Inventory:Listed.
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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